Hyaluronan nanoplatelets exert an intrinsic anti-inflammatory activity in a rat model of bladder painful syndrome/interstitial cystitis

Glycosaminoglycan (GAG) replenishment therapy consists of the instillation of GAG solutions directly in the bladder to alleviate Bladder Painful Syndrome/Interstitial Cystitis (BPS/IC). However, several issues were reported with this strategy because the GAG solutions are rapidly eliminated from the...

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Veröffentlicht in:	Journal of controlled release 2023-04, Vol.356, p.434-447
Hauptverfasser:	Diaz-Salmeron, Raul, Cailleau, Catherine, Denis, Stéphanie, Ponchel, Gilles, Bouchemal, Kawthar
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravesical Animals Anti-Inflammatory Agents - therapeutic use Bladder Cystitis, Interstitial - drug therapy Glycosaminoglycans - therapeutic use Hyaluronic acid Hyaluronic Acid - therapeutic use Inflammation - drug therapy Nanoparticles Nanoplatelets Rats Self-assemblies Urinary Bladder
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