Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conf...
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Veröffentlicht in: | Neuroscience and biobehavioral reviews 2023-06, Vol.149, p.105150-105150, Article 105150 |
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description | Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary.
•This article describes the clinical consequences related to COVID-19 infection.•People those who tested positive for COVID-19 had more brain shrinkage.•The damage occurs in areas of the brain that are associated with odour, etc.•Patients after COVID-19, a deepening of persistent neurological signs is necessary. |
doi_str_mv | 10.1016/j.neubiorev.2023.105150 |
format | Article |
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•This article describes the clinical consequences related to COVID-19 infection.•People those who tested positive for COVID-19 had more brain shrinkage.•The damage occurs in areas of the brain that are associated with odour, etc.•Patients after COVID-19, a deepening of persistent neurological signs is necessary.</description><identifier>ISSN: 0149-7634</identifier><identifier>EISSN: 1873-7528</identifier><identifier>DOI: 10.1016/j.neubiorev.2023.105150</identifier><identifier>PMID: 37004892</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Brain ; Brain shrinks ; Communicable Disease Control ; COVID-19 ; Functional connectivity ; Gray matter ; Humans ; Neurological disorders ; SARS-CoV-2 ; Stroke</subject><ispartof>Neuroscience and biobehavioral reviews, 2023-06, Vol.149, p.105150-105150, Article 105150</ispartof><rights>2023 Elsevier Ltd</rights><rights>Copyright © 2023 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-3b469385c33bdc22b0f52f24012dcbe99e2866fc659e18447a267ac097be87233</citedby><cites>FETCH-LOGICAL-c420t-3b469385c33bdc22b0f52f24012dcbe99e2866fc659e18447a267ac097be87233</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.neubiorev.2023.105150$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37004892$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, Puranam Revanth</creatorcontrib><creatorcontrib>Shilpa, B.</creatorcontrib><creatorcontrib>Jha, Rajesh Kumar</creatorcontrib><title>Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain</title><title>Neuroscience and biobehavioral reviews</title><addtitle>Neurosci Biobehav Rev</addtitle><description>Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary.
•This article describes the clinical consequences related to COVID-19 infection.•People those who tested positive for COVID-19 had more brain shrinkage.•The damage occurs in areas of the brain that are associated with odour, etc.•Patients after COVID-19, a deepening of persistent neurological signs is necessary.</description><subject>Brain</subject><subject>Brain shrinks</subject><subject>Communicable Disease Control</subject><subject>COVID-19</subject><subject>Functional connectivity</subject><subject>Gray matter</subject><subject>Humans</subject><subject>Neurological disorders</subject><subject>SARS-CoV-2</subject><subject>Stroke</subject><issn>0149-7634</issn><issn>1873-7528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EglL4BfCSTcr4kdhhVyoelZBAvLaW40xUlzyKnVbi70lVYMtqpNG5dzSHkHMGEwYsu1xOWlwXvgu4mXDgYtimLIU9MmJaiUSlXO-TETCZJyoT8ogcx7gEAA4iPSRHQgFInfMReboO1re09LELJYZ4RefNyrqedhVtfF3Sl-nzSzLr3hNOG_tF4yL49oNG3GCwNV3Z0Mct2y-QFtuqE3JQ2Tri6c8ck7fbm9fZffLweDefTR8SJzn0iShklgudOiGK0nFeQJXyiktgvHQF5jlynWWVy9IcmZZSWZ4p6yBXBWrFhRiTi13vKnSfa4y9aXx0WNe2xW4dDVe5zHSqGQyo2qEudDEGrMwq-MaGL8PAbHWapfnTabY6zU7nkDz7ObIuGiz_cr_-BmC6A3B4deMxmOg8tg5LH9D1puz8v0e-AQ6biIE</recordid><startdate>202306</startdate><enddate>202306</enddate><creator>Kumar, Puranam Revanth</creator><creator>Shilpa, B.</creator><creator>Jha, Rajesh Kumar</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202306</creationdate><title>Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain</title><author>Kumar, Puranam Revanth ; Shilpa, B. ; Jha, Rajesh Kumar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-3b469385c33bdc22b0f52f24012dcbe99e2866fc659e18447a267ac097be87233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Brain</topic><topic>Brain shrinks</topic><topic>Communicable Disease Control</topic><topic>COVID-19</topic><topic>Functional connectivity</topic><topic>Gray matter</topic><topic>Humans</topic><topic>Neurological disorders</topic><topic>SARS-CoV-2</topic><topic>Stroke</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumar, Puranam Revanth</creatorcontrib><creatorcontrib>Shilpa, B.</creatorcontrib><creatorcontrib>Jha, Rajesh Kumar</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience and biobehavioral reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, Puranam Revanth</au><au>Shilpa, B.</au><au>Jha, Rajesh Kumar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain</atitle><jtitle>Neuroscience and biobehavioral reviews</jtitle><addtitle>Neurosci Biobehav Rev</addtitle><date>2023-06</date><risdate>2023</risdate><volume>149</volume><spage>105150</spage><epage>105150</epage><pages>105150-105150</pages><artnum>105150</artnum><issn>0149-7634</issn><eissn>1873-7528</eissn><abstract>Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary.
•This article describes the clinical consequences related to COVID-19 infection.•People those who tested positive for COVID-19 had more brain shrinkage.•The damage occurs in areas of the brain that are associated with odour, etc.•Patients after COVID-19, a deepening of persistent neurological signs is necessary.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>37004892</pmid><doi>10.1016/j.neubiorev.2023.105150</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Brain Brain shrinks Communicable Disease Control COVID-19 Functional connectivity Gray matter Humans Neurological disorders SARS-CoV-2 Stroke |
title | Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
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