Use of extracorporeal therapies to treat life-threatening intoxications
Toxic ingestions are a significant cause of pediatric morbidity and mortality, with some requiring extracorporeal removal for therapy. Given the emergent and life-threatening nature of such scenarios, it is paramount that clinicians caring for intoxicated children be familiar with the subject. This...
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| Veröffentlicht in: | Pediatric nephrology (Berlin, West) West), 2024-01, Vol.39 (1), p.105-113 |
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| creator | Deville, Kyle Charlton, Nathan Askenazi, David |
| description | Toxic ingestions are a significant cause of pediatric morbidity and mortality, with some requiring extracorporeal removal for therapy. Given the emergent and life-threatening nature of such scenarios, it is paramount that clinicians caring for intoxicated children be familiar with the subject. This review summarizes the following: (a) the properties of a substance which lend it amenable to removal; (b) the current extracorporeal treatment modalities available for such removal (of which hemodialysis is typically the ideal choice); (c) an introduction and framework to use a quick reference guide from the Extrip organization, which has a website available to guide clinicians’ rapid decisions; and (d) new membranes/approaches that may optimize clearance of certain intoxications. |
| doi_str_mv | 10.1007/s00467-023-05937-7 |
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| subjects | Blood Care and treatment Drugs Drunkenness (Criminal law) Educational Review Evaluation Hemodialysis Hemodynamics Medicine Medicine & Public Health Morbidity Nephrology Patient outcomes Pediatrics Proteins Toxins Urology |
| title | Use of extracorporeal therapies to treat life-threatening intoxications |
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