The involvement of Aurora‐A and p53 in oxaliplatin‐resistant colon cancer cells

Resistance to chemotherapy is the deadlock in cancer treatment. In this study, we used wild‐type LOVO (LOVOWT), a human colon cancer cell line, and the oxaliplatin‐resistant sub‐clone LOVOOR cells to investigate the molecular mechanisms of the development of drug resistance in colon cancer. Compared...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular biochemistry 2023-04, Vol.124 (4), p.619-632
Hauptverfasser:	Chen, Mei‐Chih, Yang, Bing‐Ze, Kuo, Wei‐Wen, Wu, Shih‐Hsin, Wang, Tso‐Fu, Yeh, Yu‐Lan, Chen, Ming‐Cheng, Huang, Chih‐Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Aurora‐A Cancer Cell Line, Tumor Cell proliferation Chemotherapy Colon cancer Colonic Neoplasms - drug therapy Colonic Neoplasms - genetics Colonic Neoplasms - metabolism Colorectal cancer Drug resistance Drug Resistance, Neoplasm Humans Immunofluorescence Kinases Molecular modelling Oxaliplatin Oxaliplatin - pharmacology p53 p53 Protein Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!