Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry

Introduction: The aim of this study was to evaluate the effects of baseline anemia and anemia following revascularization on outcomes in patients with unprotected left main coronary artery (ULMCA) disease. Methods: This was a retrospective, multicenter, observational study conducted between January...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cardiology 2023-07, Vol.148 (3), p.173-186
Hauptverfasser: Daoulah, Amin, Jameel Naser, Maryam, Hersi, Ahmad, Yousif, Nooraldaem, Alasmari, Abdulaziz, Almahmeed, Wael, AlZahrani, Hazza A., Aljohar, Alwaleed, Alshehri, Mohammed, Alzahrani, Badr, Basudan, Duna, Alosaimi, Hind, Abuelatta, Reda, Al Garni, Turki, Ghani, Mohamed Ajaz, Amin, Haitham, Noor, Husam A., Hashmani, Shahrukh, Al Nasser, Faisal Omar M., Kazim, Hameedullah M., Wael Refaat, Wael Refaat, Selim, Ehab, Jamjoom, Ahmed, El-Sayed, Osama, Hassan, Taher, Dahdouh, Ziad, Aithal, Jairam, Diab, Ahmed, Ibrahim, Ahmed M., Elganady, Abdelmaksoud, Qutub, Mohammed A., Alama, Mohamed N., Abohasan, Abdulwali, Tawfik, Wael, Balghith, Mohammed, Abualnaja, Seraj, Fathey Hussien, Adnan, Abdulhabeeb, Ibrahim A.M., Ahmad, Osama, Ramadan, Mohamed, Alqahtani, Abdulrahman H., Al Samadi, Faisal, Qenawi, Wael, Shawky, Ahmed, Ghonim, Ahmed A., Arafat, Amr A., Elmahrouk, Ahmed, Elmahrouk, Youssef, Hiremath, Niranjan, Shawky, Abeer M., Asrar, Farhan M., Farghali, Tarek, Altnji, Issam, Aljohani, Khalid, Alotaiby, Mohammed, Alqahtani, Abdulrahman M., Lotfi, Amir
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 186
container_issue 3
container_start_page 173
container_title Cardiology
container_volume 148
creator Daoulah, Amin
Jameel Naser, Maryam
Hersi, Ahmad
Yousif, Nooraldaem
Alasmari, Abdulaziz
Almahmeed, Wael
AlZahrani, Hazza A.
Aljohar, Alwaleed
Alshehri, Mohammed
Alzahrani, Badr
Basudan, Duna
Alosaimi, Hind
Abuelatta, Reda
Al Garni, Turki
Ghani, Mohamed Ajaz
Amin, Haitham
Noor, Husam A.
Hashmani, Shahrukh
Al Nasser, Faisal Omar M.
Kazim, Hameedullah M.
Wael Refaat, Wael Refaat
Selim, Ehab
Jamjoom, Ahmed
El-Sayed, Osama
Hassan, Taher
Dahdouh, Ziad
Aithal, Jairam
Diab, Ahmed
Ibrahim, Ahmed M.
Elganady, Abdelmaksoud
Qutub, Mohammed A.
Alama, Mohamed N.
Abohasan, Abdulwali
Tawfik, Wael
Balghith, Mohammed
Abualnaja, Seraj
Fathey Hussien, Adnan
Abdulhabeeb, Ibrahim A.M.
Ahmad, Osama
Ramadan, Mohamed
Alqahtani, Abdulrahman H.
Al Samadi, Faisal
Qenawi, Wael
Shawky, Ahmed
Ghonim, Ahmed A.
Arafat, Amr A.
Elmahrouk, Ahmed
Elmahrouk, Youssef
Hiremath, Niranjan
Shawky, Abeer M.
Asrar, Farhan M.
Farghali, Tarek
Altnji, Issam
Aljohani, Khalid
Alotaiby, Mohammed
Alqahtani, Abdulrahman M.
Lotfi, Amir
description Introduction: The aim of this study was to evaluate the effects of baseline anemia and anemia following revascularization on outcomes in patients with unprotected left main coronary artery (ULMCA) disease. Methods: This was a retrospective, multicenter, observational study conducted between January 2015 and December 2019. The data on patients with ULMCA who underwent revascularization through percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) were stratified by the hemoglobin level at baseline into anemic and non-anemic groups to compare in-hospital events. The pre-discharge hemoglobin following revascularization was categorized into very low (
doi_str_mv 10.1159/000530305
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2791704090</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2791704090</sourcerecordid><originalsourceid>FETCH-LOGICAL-c334t-e4a4373b41087742fe3edc0c3d49e99b7e77711ef198e6c805744a2e173547dd3</originalsourceid><addsrcrecordid>eNpt0M1LwzAYBvAgipvTg3eRghc9VJMmaRpvY-oUJpOh4K1k6dtZ7cdMUmX-9UY6B4KnJC-_PAkPQocEnxPC5QXGmFNMMd9CfcIiEkrByTbq-3kSxpREPbRn7as_MsGiXdSjsYxjHvE-ep62TjcV2KDJgwnkLrhXRR3M4ENZ3ZbKFF_KFU0d-OGD30HtbPBZuJdgWENVqMtg3JZ_by4K68xqH-3kqrRwsF4H6Onm-nF0G06m47vRcBJqSpkLgSlGBZ0zghPhP5cDhUxjTTMmQcq5ACEEIZATmUCsE8wFYyoCIihnIsvoAJ12uUvTvLdgXVoVVkNZqhqa1qaRkERghiX29Kyj2jTWGsjTpSkqZVYpwelPkemmSG-P17HtvIJsI3-b8-CkA2_KLMBswGh21UWkyyz36uhftX7lG8pzgNo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2791704090</pqid></control><display><type>article</type><title>Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry</title><source>Karger Journals</source><creator>Daoulah, Amin ; Jameel Naser, Maryam ; Hersi, Ahmad ; Yousif, Nooraldaem ; Alasmari, Abdulaziz ; Almahmeed, Wael ; AlZahrani, Hazza A. ; Aljohar, Alwaleed ; Alshehri, Mohammed ; Alzahrani, Badr ; Basudan, Duna ; Alosaimi, Hind ; Abuelatta, Reda ; Al Garni, Turki ; Ghani, Mohamed Ajaz ; Amin, Haitham ; Noor, Husam A. ; Hashmani, Shahrukh ; Al Nasser, Faisal Omar M. ; Kazim, Hameedullah M. ; Wael Refaat, Wael Refaat ; Selim, Ehab ; Jamjoom, Ahmed ; El-Sayed, Osama ; Hassan, Taher ; Dahdouh, Ziad ; Aithal, Jairam ; Diab, Ahmed ; Ibrahim, Ahmed M. ; Elganady, Abdelmaksoud ; Qutub, Mohammed A. ; Alama, Mohamed N. ; Abohasan, Abdulwali ; Tawfik, Wael ; Balghith, Mohammed ; Abualnaja, Seraj ; Fathey Hussien, Adnan ; Abdulhabeeb, Ibrahim A.M. ; Ahmad, Osama ; Ramadan, Mohamed ; Alqahtani, Abdulrahman H. ; Al Samadi, Faisal ; Qenawi, Wael ; Shawky, Ahmed ; Ghonim, Ahmed A. ; Arafat, Amr A. ; Elmahrouk, Ahmed ; Elmahrouk, Youssef ; Hiremath, Niranjan ; Shawky, Abeer M. ; Asrar, Farhan M. ; Farghali, Tarek ; Altnji, Issam ; Aljohani, Khalid ; Alotaiby, Mohammed ; Alqahtani, Abdulrahman M. ; Lotfi, Amir</creator><creatorcontrib>Daoulah, Amin ; Jameel Naser, Maryam ; Hersi, Ahmad ; Yousif, Nooraldaem ; Alasmari, Abdulaziz ; Almahmeed, Wael ; AlZahrani, Hazza A. ; Aljohar, Alwaleed ; Alshehri, Mohammed ; Alzahrani, Badr ; Basudan, Duna ; Alosaimi, Hind ; Abuelatta, Reda ; Al Garni, Turki ; Ghani, Mohamed Ajaz ; Amin, Haitham ; Noor, Husam A. ; Hashmani, Shahrukh ; Al Nasser, Faisal Omar M. ; Kazim, Hameedullah M. ; Wael Refaat, Wael Refaat ; Selim, Ehab ; Jamjoom, Ahmed ; El-Sayed, Osama ; Hassan, Taher ; Dahdouh, Ziad ; Aithal, Jairam ; Diab, Ahmed ; Ibrahim, Ahmed M. ; Elganady, Abdelmaksoud ; Qutub, Mohammed A. ; Alama, Mohamed N. ; Abohasan, Abdulwali ; Tawfik, Wael ; Balghith, Mohammed ; Abualnaja, Seraj ; Fathey Hussien, Adnan ; Abdulhabeeb, Ibrahim A.M. ; Ahmad, Osama ; Ramadan, Mohamed ; Alqahtani, Abdulrahman H. ; Al Samadi, Faisal ; Qenawi, Wael ; Shawky, Ahmed ; Ghonim, Ahmed A. ; Arafat, Amr A. ; Elmahrouk, Ahmed ; Elmahrouk, Youssef ; Hiremath, Niranjan ; Shawky, Abeer M. ; Asrar, Farhan M. ; Farghali, Tarek ; Altnji, Issam ; Aljohani, Khalid ; Alotaiby, Mohammed ; Alqahtani, Abdulrahman M. ; Lotfi, Amir</creatorcontrib><description>Introduction: The aim of this study was to evaluate the effects of baseline anemia and anemia following revascularization on outcomes in patients with unprotected left main coronary artery (ULMCA) disease. Methods: This was a retrospective, multicenter, observational study conducted between January 2015 and December 2019. The data on patients with ULMCA who underwent revascularization through percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) were stratified by the hemoglobin level at baseline into anemic and non-anemic groups to compare in-hospital events. The pre-discharge hemoglobin following revascularization was categorized into very low (&lt;80 g/L for men and women), low (≥80 and ≤119 g/L for women and ≤129 g/L for men), and normal (≥130 g/L for men and ≥120 g/L for women) to assess impact on follow-up outcomes. Results: A total of 2,138 patients were included, 796 (37.2%) of whom had anemia at baseline. A total of 319 developed anemia after revascularization and moved from being non-anemic at baseline to anemic at discharge. There was no difference in hospital major adverse cardiac and cerebrovascular event (MACCE) and mortality between CABG and PCI in anemic patients. At a median follow-up time of 20 months (interquartile range [IQR]: 27), patients with pre-discharge anemia who underwent PCI had a higher incidence of congestive heart failure (CHF) (p &lt; 0.0001), and those who underwent CABG had significantly higher follow-up mortality (HR: 9.85 (95% CI: 2.53–38.43), p = 0.001). Conclusion: In this Gulf LM study, baseline anemia had no impact upon in-hospital MACCE and total mortality following revascularization (PCI or CABG). However, pre-discharge anemia is associated with worse outcomes after ULMCA disease revascularization, with significantly higher all-cause mortality in patients who had CABG, and a higher incidence of CHF in PCI patients, at a median follow-up time of 20 months (IQR: 27).</description><identifier>ISSN: 0008-6312</identifier><identifier>EISSN: 1421-9751</identifier><identifier>DOI: 10.1159/000530305</identifier><identifier>PMID: 36966525</identifier><language>eng</language><publisher>Basel, Switzerland</publisher><subject>CAD and AMI: Research Article</subject><ispartof>Cardiology, 2023-07, Vol.148 (3), p.173-186</ispartof><rights>2023 S. Karger AG, Basel</rights><rights>2023 S. Karger AG, Basel.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c334t-e4a4373b41087742fe3edc0c3d49e99b7e77711ef198e6c805744a2e173547dd3</citedby><cites>FETCH-LOGICAL-c334t-e4a4373b41087742fe3edc0c3d49e99b7e77711ef198e6c805744a2e173547dd3</cites><orcidid>0000-0002-5775-5557 ; 0000-0003-1363-3619</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,2423,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36966525$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Daoulah, Amin</creatorcontrib><creatorcontrib>Jameel Naser, Maryam</creatorcontrib><creatorcontrib>Hersi, Ahmad</creatorcontrib><creatorcontrib>Yousif, Nooraldaem</creatorcontrib><creatorcontrib>Alasmari, Abdulaziz</creatorcontrib><creatorcontrib>Almahmeed, Wael</creatorcontrib><creatorcontrib>AlZahrani, Hazza A.</creatorcontrib><creatorcontrib>Aljohar, Alwaleed</creatorcontrib><creatorcontrib>Alshehri, Mohammed</creatorcontrib><creatorcontrib>Alzahrani, Badr</creatorcontrib><creatorcontrib>Basudan, Duna</creatorcontrib><creatorcontrib>Alosaimi, Hind</creatorcontrib><creatorcontrib>Abuelatta, Reda</creatorcontrib><creatorcontrib>Al Garni, Turki</creatorcontrib><creatorcontrib>Ghani, Mohamed Ajaz</creatorcontrib><creatorcontrib>Amin, Haitham</creatorcontrib><creatorcontrib>Noor, Husam A.</creatorcontrib><creatorcontrib>Hashmani, Shahrukh</creatorcontrib><creatorcontrib>Al Nasser, Faisal Omar M.</creatorcontrib><creatorcontrib>Kazim, Hameedullah M.</creatorcontrib><creatorcontrib>Wael Refaat, Wael Refaat</creatorcontrib><creatorcontrib>Selim, Ehab</creatorcontrib><creatorcontrib>Jamjoom, Ahmed</creatorcontrib><creatorcontrib>El-Sayed, Osama</creatorcontrib><creatorcontrib>Hassan, Taher</creatorcontrib><creatorcontrib>Dahdouh, Ziad</creatorcontrib><creatorcontrib>Aithal, Jairam</creatorcontrib><creatorcontrib>Diab, Ahmed</creatorcontrib><creatorcontrib>Ibrahim, Ahmed M.</creatorcontrib><creatorcontrib>Elganady, Abdelmaksoud</creatorcontrib><creatorcontrib>Qutub, Mohammed A.</creatorcontrib><creatorcontrib>Alama, Mohamed N.</creatorcontrib><creatorcontrib>Abohasan, Abdulwali</creatorcontrib><creatorcontrib>Tawfik, Wael</creatorcontrib><creatorcontrib>Balghith, Mohammed</creatorcontrib><creatorcontrib>Abualnaja, Seraj</creatorcontrib><creatorcontrib>Fathey Hussien, Adnan</creatorcontrib><creatorcontrib>Abdulhabeeb, Ibrahim A.M.</creatorcontrib><creatorcontrib>Ahmad, Osama</creatorcontrib><creatorcontrib>Ramadan, Mohamed</creatorcontrib><creatorcontrib>Alqahtani, Abdulrahman H.</creatorcontrib><creatorcontrib>Al Samadi, Faisal</creatorcontrib><creatorcontrib>Qenawi, Wael</creatorcontrib><creatorcontrib>Shawky, Ahmed</creatorcontrib><creatorcontrib>Ghonim, Ahmed A.</creatorcontrib><creatorcontrib>Arafat, Amr A.</creatorcontrib><creatorcontrib>Elmahrouk, Ahmed</creatorcontrib><creatorcontrib>Elmahrouk, Youssef</creatorcontrib><creatorcontrib>Hiremath, Niranjan</creatorcontrib><creatorcontrib>Shawky, Abeer M.</creatorcontrib><creatorcontrib>Asrar, Farhan M.</creatorcontrib><creatorcontrib>Farghali, Tarek</creatorcontrib><creatorcontrib>Altnji, Issam</creatorcontrib><creatorcontrib>Aljohani, Khalid</creatorcontrib><creatorcontrib>Alotaiby, Mohammed</creatorcontrib><creatorcontrib>Alqahtani, Abdulrahman M.</creatorcontrib><creatorcontrib>Lotfi, Amir</creatorcontrib><title>Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry</title><title>Cardiology</title><addtitle>Cardiology</addtitle><description>Introduction: The aim of this study was to evaluate the effects of baseline anemia and anemia following revascularization on outcomes in patients with unprotected left main coronary artery (ULMCA) disease. Methods: This was a retrospective, multicenter, observational study conducted between January 2015 and December 2019. The data on patients with ULMCA who underwent revascularization through percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) were stratified by the hemoglobin level at baseline into anemic and non-anemic groups to compare in-hospital events. The pre-discharge hemoglobin following revascularization was categorized into very low (&lt;80 g/L for men and women), low (≥80 and ≤119 g/L for women and ≤129 g/L for men), and normal (≥130 g/L for men and ≥120 g/L for women) to assess impact on follow-up outcomes. Results: A total of 2,138 patients were included, 796 (37.2%) of whom had anemia at baseline. A total of 319 developed anemia after revascularization and moved from being non-anemic at baseline to anemic at discharge. There was no difference in hospital major adverse cardiac and cerebrovascular event (MACCE) and mortality between CABG and PCI in anemic patients. At a median follow-up time of 20 months (interquartile range [IQR]: 27), patients with pre-discharge anemia who underwent PCI had a higher incidence of congestive heart failure (CHF) (p &lt; 0.0001), and those who underwent CABG had significantly higher follow-up mortality (HR: 9.85 (95% CI: 2.53–38.43), p = 0.001). Conclusion: In this Gulf LM study, baseline anemia had no impact upon in-hospital MACCE and total mortality following revascularization (PCI or CABG). However, pre-discharge anemia is associated with worse outcomes after ULMCA disease revascularization, with significantly higher all-cause mortality in patients who had CABG, and a higher incidence of CHF in PCI patients, at a median follow-up time of 20 months (IQR: 27).</description><subject>CAD and AMI: Research Article</subject><issn>0008-6312</issn><issn>1421-9751</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpt0M1LwzAYBvAgipvTg3eRghc9VJMmaRpvY-oUJpOh4K1k6dtZ7cdMUmX-9UY6B4KnJC-_PAkPQocEnxPC5QXGmFNMMd9CfcIiEkrByTbq-3kSxpREPbRn7as_MsGiXdSjsYxjHvE-ep62TjcV2KDJgwnkLrhXRR3M4ENZ3ZbKFF_KFU0d-OGD30HtbPBZuJdgWENVqMtg3JZ_by4K68xqH-3kqrRwsF4H6Onm-nF0G06m47vRcBJqSpkLgSlGBZ0zghPhP5cDhUxjTTMmQcq5ACEEIZATmUCsE8wFYyoCIihnIsvoAJ12uUvTvLdgXVoVVkNZqhqa1qaRkERghiX29Kyj2jTWGsjTpSkqZVYpwelPkemmSG-P17HtvIJsI3-b8-CkA2_KLMBswGh21UWkyyz36uhftX7lG8pzgNo</recordid><startdate>20230701</startdate><enddate>20230701</enddate><creator>Daoulah, Amin</creator><creator>Jameel Naser, Maryam</creator><creator>Hersi, Ahmad</creator><creator>Yousif, Nooraldaem</creator><creator>Alasmari, Abdulaziz</creator><creator>Almahmeed, Wael</creator><creator>AlZahrani, Hazza A.</creator><creator>Aljohar, Alwaleed</creator><creator>Alshehri, Mohammed</creator><creator>Alzahrani, Badr</creator><creator>Basudan, Duna</creator><creator>Alosaimi, Hind</creator><creator>Abuelatta, Reda</creator><creator>Al Garni, Turki</creator><creator>Ghani, Mohamed Ajaz</creator><creator>Amin, Haitham</creator><creator>Noor, Husam A.</creator><creator>Hashmani, Shahrukh</creator><creator>Al Nasser, Faisal Omar M.</creator><creator>Kazim, Hameedullah M.</creator><creator>Wael Refaat, Wael Refaat</creator><creator>Selim, Ehab</creator><creator>Jamjoom, Ahmed</creator><creator>El-Sayed, Osama</creator><creator>Hassan, Taher</creator><creator>Dahdouh, Ziad</creator><creator>Aithal, Jairam</creator><creator>Diab, Ahmed</creator><creator>Ibrahim, Ahmed M.</creator><creator>Elganady, Abdelmaksoud</creator><creator>Qutub, Mohammed A.</creator><creator>Alama, Mohamed N.</creator><creator>Abohasan, Abdulwali</creator><creator>Tawfik, Wael</creator><creator>Balghith, Mohammed</creator><creator>Abualnaja, Seraj</creator><creator>Fathey Hussien, Adnan</creator><creator>Abdulhabeeb, Ibrahim A.M.</creator><creator>Ahmad, Osama</creator><creator>Ramadan, Mohamed</creator><creator>Alqahtani, Abdulrahman H.</creator><creator>Al Samadi, Faisal</creator><creator>Qenawi, Wael</creator><creator>Shawky, Ahmed</creator><creator>Ghonim, Ahmed A.</creator><creator>Arafat, Amr A.</creator><creator>Elmahrouk, Ahmed</creator><creator>Elmahrouk, Youssef</creator><creator>Hiremath, Niranjan</creator><creator>Shawky, Abeer M.</creator><creator>Asrar, Farhan M.</creator><creator>Farghali, Tarek</creator><creator>Altnji, Issam</creator><creator>Aljohani, Khalid</creator><creator>Alotaiby, Mohammed</creator><creator>Alqahtani, Abdulrahman M.</creator><creator>Lotfi, Amir</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5775-5557</orcidid><orcidid>https://orcid.org/0000-0003-1363-3619</orcidid></search><sort><creationdate>20230701</creationdate><title>Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry</title><author>Daoulah, Amin ; Jameel Naser, Maryam ; Hersi, Ahmad ; Yousif, Nooraldaem ; Alasmari, Abdulaziz ; Almahmeed, Wael ; AlZahrani, Hazza A. ; Aljohar, Alwaleed ; Alshehri, Mohammed ; Alzahrani, Badr ; Basudan, Duna ; Alosaimi, Hind ; Abuelatta, Reda ; Al Garni, Turki ; Ghani, Mohamed Ajaz ; Amin, Haitham ; Noor, Husam A. ; Hashmani, Shahrukh ; Al Nasser, Faisal Omar M. ; Kazim, Hameedullah M. ; Wael Refaat, Wael Refaat ; Selim, Ehab ; Jamjoom, Ahmed ; El-Sayed, Osama ; Hassan, Taher ; Dahdouh, Ziad ; Aithal, Jairam ; Diab, Ahmed ; Ibrahim, Ahmed M. ; Elganady, Abdelmaksoud ; Qutub, Mohammed A. ; Alama, Mohamed N. ; Abohasan, Abdulwali ; Tawfik, Wael ; Balghith, Mohammed ; Abualnaja, Seraj ; Fathey Hussien, Adnan ; Abdulhabeeb, Ibrahim A.M. ; Ahmad, Osama ; Ramadan, Mohamed ; Alqahtani, Abdulrahman H. ; Al Samadi, Faisal ; Qenawi, Wael ; Shawky, Ahmed ; Ghonim, Ahmed A. ; Arafat, Amr A. ; Elmahrouk, Ahmed ; Elmahrouk, Youssef ; Hiremath, Niranjan ; Shawky, Abeer M. ; Asrar, Farhan M. ; Farghali, Tarek ; Altnji, Issam ; Aljohani, Khalid ; Alotaiby, Mohammed ; Alqahtani, Abdulrahman M. ; Lotfi, Amir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c334t-e4a4373b41087742fe3edc0c3d49e99b7e77711ef198e6c805744a2e173547dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CAD and AMI: Research Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Daoulah, Amin</creatorcontrib><creatorcontrib>Jameel Naser, Maryam</creatorcontrib><creatorcontrib>Hersi, Ahmad</creatorcontrib><creatorcontrib>Yousif, Nooraldaem</creatorcontrib><creatorcontrib>Alasmari, Abdulaziz</creatorcontrib><creatorcontrib>Almahmeed, Wael</creatorcontrib><creatorcontrib>AlZahrani, Hazza A.</creatorcontrib><creatorcontrib>Aljohar, Alwaleed</creatorcontrib><creatorcontrib>Alshehri, Mohammed</creatorcontrib><creatorcontrib>Alzahrani, Badr</creatorcontrib><creatorcontrib>Basudan, Duna</creatorcontrib><creatorcontrib>Alosaimi, Hind</creatorcontrib><creatorcontrib>Abuelatta, Reda</creatorcontrib><creatorcontrib>Al Garni, Turki</creatorcontrib><creatorcontrib>Ghani, Mohamed Ajaz</creatorcontrib><creatorcontrib>Amin, Haitham</creatorcontrib><creatorcontrib>Noor, Husam A.</creatorcontrib><creatorcontrib>Hashmani, Shahrukh</creatorcontrib><creatorcontrib>Al Nasser, Faisal Omar M.</creatorcontrib><creatorcontrib>Kazim, Hameedullah M.</creatorcontrib><creatorcontrib>Wael Refaat, Wael Refaat</creatorcontrib><creatorcontrib>Selim, Ehab</creatorcontrib><creatorcontrib>Jamjoom, Ahmed</creatorcontrib><creatorcontrib>El-Sayed, Osama</creatorcontrib><creatorcontrib>Hassan, Taher</creatorcontrib><creatorcontrib>Dahdouh, Ziad</creatorcontrib><creatorcontrib>Aithal, Jairam</creatorcontrib><creatorcontrib>Diab, Ahmed</creatorcontrib><creatorcontrib>Ibrahim, Ahmed M.</creatorcontrib><creatorcontrib>Elganady, Abdelmaksoud</creatorcontrib><creatorcontrib>Qutub, Mohammed A.</creatorcontrib><creatorcontrib>Alama, Mohamed N.</creatorcontrib><creatorcontrib>Abohasan, Abdulwali</creatorcontrib><creatorcontrib>Tawfik, Wael</creatorcontrib><creatorcontrib>Balghith, Mohammed</creatorcontrib><creatorcontrib>Abualnaja, Seraj</creatorcontrib><creatorcontrib>Fathey Hussien, Adnan</creatorcontrib><creatorcontrib>Abdulhabeeb, Ibrahim A.M.</creatorcontrib><creatorcontrib>Ahmad, Osama</creatorcontrib><creatorcontrib>Ramadan, Mohamed</creatorcontrib><creatorcontrib>Alqahtani, Abdulrahman H.</creatorcontrib><creatorcontrib>Al Samadi, Faisal</creatorcontrib><creatorcontrib>Qenawi, Wael</creatorcontrib><creatorcontrib>Shawky, Ahmed</creatorcontrib><creatorcontrib>Ghonim, Ahmed A.</creatorcontrib><creatorcontrib>Arafat, Amr A.</creatorcontrib><creatorcontrib>Elmahrouk, Ahmed</creatorcontrib><creatorcontrib>Elmahrouk, Youssef</creatorcontrib><creatorcontrib>Hiremath, Niranjan</creatorcontrib><creatorcontrib>Shawky, Abeer M.</creatorcontrib><creatorcontrib>Asrar, Farhan M.</creatorcontrib><creatorcontrib>Farghali, Tarek</creatorcontrib><creatorcontrib>Altnji, Issam</creatorcontrib><creatorcontrib>Aljohani, Khalid</creatorcontrib><creatorcontrib>Alotaiby, Mohammed</creatorcontrib><creatorcontrib>Alqahtani, Abdulrahman M.</creatorcontrib><creatorcontrib>Lotfi, Amir</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Daoulah, Amin</au><au>Jameel Naser, Maryam</au><au>Hersi, Ahmad</au><au>Yousif, Nooraldaem</au><au>Alasmari, Abdulaziz</au><au>Almahmeed, Wael</au><au>AlZahrani, Hazza A.</au><au>Aljohar, Alwaleed</au><au>Alshehri, Mohammed</au><au>Alzahrani, Badr</au><au>Basudan, Duna</au><au>Alosaimi, Hind</au><au>Abuelatta, Reda</au><au>Al Garni, Turki</au><au>Ghani, Mohamed Ajaz</au><au>Amin, Haitham</au><au>Noor, Husam A.</au><au>Hashmani, Shahrukh</au><au>Al Nasser, Faisal Omar M.</au><au>Kazim, Hameedullah M.</au><au>Wael Refaat, Wael Refaat</au><au>Selim, Ehab</au><au>Jamjoom, Ahmed</au><au>El-Sayed, Osama</au><au>Hassan, Taher</au><au>Dahdouh, Ziad</au><au>Aithal, Jairam</au><au>Diab, Ahmed</au><au>Ibrahim, Ahmed M.</au><au>Elganady, Abdelmaksoud</au><au>Qutub, Mohammed A.</au><au>Alama, Mohamed N.</au><au>Abohasan, Abdulwali</au><au>Tawfik, Wael</au><au>Balghith, Mohammed</au><au>Abualnaja, Seraj</au><au>Fathey Hussien, Adnan</au><au>Abdulhabeeb, Ibrahim A.M.</au><au>Ahmad, Osama</au><au>Ramadan, Mohamed</au><au>Alqahtani, Abdulrahman H.</au><au>Al Samadi, Faisal</au><au>Qenawi, Wael</au><au>Shawky, Ahmed</au><au>Ghonim, Ahmed A.</au><au>Arafat, Amr A.</au><au>Elmahrouk, Ahmed</au><au>Elmahrouk, Youssef</au><au>Hiremath, Niranjan</au><au>Shawky, Abeer M.</au><au>Asrar, Farhan M.</au><au>Farghali, Tarek</au><au>Altnji, Issam</au><au>Aljohani, Khalid</au><au>Alotaiby, Mohammed</au><au>Alqahtani, Abdulrahman M.</au><au>Lotfi, Amir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry</atitle><jtitle>Cardiology</jtitle><addtitle>Cardiology</addtitle><date>2023-07-01</date><risdate>2023</risdate><volume>148</volume><issue>3</issue><spage>173</spage><epage>186</epage><pages>173-186</pages><issn>0008-6312</issn><eissn>1421-9751</eissn><abstract>Introduction: The aim of this study was to evaluate the effects of baseline anemia and anemia following revascularization on outcomes in patients with unprotected left main coronary artery (ULMCA) disease. Methods: This was a retrospective, multicenter, observational study conducted between January 2015 and December 2019. The data on patients with ULMCA who underwent revascularization through percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) were stratified by the hemoglobin level at baseline into anemic and non-anemic groups to compare in-hospital events. The pre-discharge hemoglobin following revascularization was categorized into very low (&lt;80 g/L for men and women), low (≥80 and ≤119 g/L for women and ≤129 g/L for men), and normal (≥130 g/L for men and ≥120 g/L for women) to assess impact on follow-up outcomes. Results: A total of 2,138 patients were included, 796 (37.2%) of whom had anemia at baseline. A total of 319 developed anemia after revascularization and moved from being non-anemic at baseline to anemic at discharge. There was no difference in hospital major adverse cardiac and cerebrovascular event (MACCE) and mortality between CABG and PCI in anemic patients. At a median follow-up time of 20 months (interquartile range [IQR]: 27), patients with pre-discharge anemia who underwent PCI had a higher incidence of congestive heart failure (CHF) (p &lt; 0.0001), and those who underwent CABG had significantly higher follow-up mortality (HR: 9.85 (95% CI: 2.53–38.43), p = 0.001). Conclusion: In this Gulf LM study, baseline anemia had no impact upon in-hospital MACCE and total mortality following revascularization (PCI or CABG). However, pre-discharge anemia is associated with worse outcomes after ULMCA disease revascularization, with significantly higher all-cause mortality in patients who had CABG, and a higher incidence of CHF in PCI patients, at a median follow-up time of 20 months (IQR: 27).</abstract><cop>Basel, Switzerland</cop><pmid>36966525</pmid><doi>10.1159/000530305</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-5775-5557</orcidid><orcidid>https://orcid.org/0000-0003-1363-3619</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0008-6312
ispartof Cardiology, 2023-07, Vol.148 (3), p.173-186
issn 0008-6312
1421-9751
language eng
recordid cdi_proquest_miscellaneous_2791704090
source Karger Journals
subjects CAD and AMI: Research Article
title Outcomes of Left Main Revascularization in Patients with Anemia: Gulf Left Main Registry
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T08%3A21%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Outcomes%20of%20Left%20Main%20Revascularization%20in%20Patients%20with%20Anemia:%20Gulf%20Left%20Main%20Registry&rft.jtitle=Cardiology&rft.au=Daoulah,%20Amin&rft.date=2023-07-01&rft.volume=148&rft.issue=3&rft.spage=173&rft.epage=186&rft.pages=173-186&rft.issn=0008-6312&rft.eissn=1421-9751&rft_id=info:doi/10.1159/000530305&rft_dat=%3Cproquest_cross%3E2791704090%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2791704090&rft_id=info:pmid/36966525&rfr_iscdi=true