The role of exosomes in pathogenesis and the therapeutic efficacy of mesenchymal stem cell-derived exosomes against Parkinson’s disease

Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease. The predominant pathology of PD is the loss of dopaminergic cells in the substantia nigra. Cell transplantation is a strategy with significant potential for treating PD; mesenchymal stem cells (MSCs) are a tremendous ther...

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Veröffentlicht in:	Neurological sciences 2023-07, Vol.44 (7), p.2277-2289
Hauptverfasser:	Abrishamdar, Maryam, Jalali, Maryam Sadat, Yazdanfar, Neda
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Biomarkers Biosynthesis Brain research Communication Dopamine Dopamine receptors Dopaminergic Neurons - pathology Exosomes Exosomes - pathology Glial cells Growth factors Humans Medicine Medicine & Public Health Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells MicroRNAs Movement disorders Nervous system Neural stem cells Neurodegeneration Neurodegenerative Diseases Neurology Neuronal-glial interactions Neuroprotection Neuroradiology Neurosciences Neurosurgery Parkinson Disease - pathology Parkinson Disease - therapy Parkinson's disease Pathogenesis Physiology Plasma Psychiatry Review Article Stem cells Substantia nigra Transplantation
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