A prospective feasibility study of uracil–tegafur and leucovorin as adjuvant chemotherapy for patients aged ≥ 80 years after curative resection of colorectal cancer, the HiSCO-03 study

Purpose There is no consensus on the safety and effectiveness of adjuvant chemotherapy for patients with stage III colorectal cancer (CRC) aged ≥ 80 years. We conducted a prospective multi-institutional phase II study of uracil–tegafur and leucovorin (UFT/LV) as adjuvant chemotherapy in this populat...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 2023-04, Vol.91 (4), p.317-324
Hauptverfasser:	Okuda, Hiroshi, Shimomura, Manabu, Ikeda, Satoshi, Nakahara, Masahiro, Miguchi, Masashi, Ishizaki, Yasuyo, Saitoh, Yasuhumi, Toyota, Kazuhiro, Sumitani, Daisuke, Shimizu, Yosuke, Takakura, Yuji, Shimizu, Wataru, Yoshimitsu, Masanori, Kodama, Shinya, Fujimori, Masahiko, Oheda, Mamoru, Kobayashi, Hironori, Ohdan, Hideki
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aged Aged, 80 and over Alanine Alanine transaminase Anemia Antineoplastic Combined Chemotherapy Protocols - adverse effects Aspartate transaminase Cancer Cancer Research Chemotherapy Chemotherapy, Adjuvant Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - surgery Confidence intervals Diarrhea Disease-Free Survival Feasibility Studies Female Humans Leucovorin Male Medicine Medicine & Public Health Mucositis Neutropenia Oldest old people Oncology Original Article Pharmacology/Toxicology Prospective Studies Tegafur Uracil
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