PPARγ inhibits small airway remodeling through mediating the polarization homeostasis of alveolar macrophages in COPD

The role of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) in alveolar macrophages(AMs) polarization homeostasis is closely associated with airway remodeling in COPD, but the definite mechanism remains unclear. In this study, elevated percentage of M1-type AMs and the expression of functionall...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2023-05, Vol.250, p.109293-109293, Article 109293
Hauptverfasser:	He, Sirong, Tian, Ruoyuan, Zhang, Xinying, Yao, Qingmei, Chen, Quan, Liu, Bicui, Liao, Lele, Gong, Yuxuan, Yang, Hua, Wang, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Remodeling Alveolar macrophages Animals COPD Homeostasis Lipopolysaccharides - pharmacology Macrophages, Alveolar - metabolism Mice Polarization homeostasis PPAR gamma - metabolism PPARγ Pulmonary Disease, Chronic Obstructive - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!