Hypothyroidism‐associated immunosuppression involves induction of galectin‐1‐producing regulatory T cells

Hypothyroidism exerts deleterious effects on immunity, but the precise role of the hypothalamic–pituitary–thyroid (HPT) axis in immunoregulatory and tolerogenic programs is barely understood. Here, we investigated the mechanisms underlying hypothyroid‐related immunosuppression by examining the regul...

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Veröffentlicht in:	The FASEB journal 2023-04, Vol.37 (4), p.e22865-n/a
Hauptverfasser:	Valli, Eduardo, Dalotto‐Moreno, Tomás, Sterle, Helena A., Méndez‐Huergo, Santiago P., Paulazo, María A., García, Silvia I., Pirola, Carlos J., Klecha, Alicia J., Rabinovich, Gabriel A., Cremaschi, Graciela A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Galectin 1 - genetics galectin‐1 hypothyroidism Hypothyroidism - metabolism Immunosuppression Therapy Mice T regulatory cells T-Lymphocytes, Regulatory - metabolism thyrotropin Thyrotropin - metabolism Thyrotropin-Releasing Hormone - pharmacology thyrotropin‐releasing hormone
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