$CD19-targeted CAR T cells in refractory antisynthetase syndrome$

CD19-targeted CAR T cells in refractory antisynthetase syndrome

Idiopathic inflammatory myopathies are a group of rare, immune-mediated diseases that primarily affect the skeletal muscle but can also involve other organs such as the lungs, skin, and joints.1 Antisynthetase syndrome comprises a major cluster of such diseases and is characterised by the developmen...

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Veröffentlicht in:	The Lancet (British edition) 2023-03, Vol.401 (10379), p.815-818
Hauptverfasser:	Müller, Fabian, Boeltz, Sebastian, Knitza, Johannes, Aigner, Michael, Völkl, Simon, Kharboutli, Soraya, Reimann, Hannah, Taubmann, Jule, Kretschmann, Sascha, Rösler, Wolf, Manger, Bernhard, Wacker, Jochen, Mougiakakos, Dimitrios, Jabari, Samir, Schröder, Rolf, Uder, Michael, Roemer, Frank, Krönke, Gerhard, Mackensen, Andreas, Schett, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Antibodies Antigens Antigens, CD19 Asparagine Blood pressure CD19 antigen Chimeric antigen receptors Creatinine Cytokines Drug delivery Drugs Glucocorticoids Glycine Health services Histidine Histopathology Humans Immunoglobulins Immunosuppressive agents Inflammation Isoleucine Joint diseases Kinases Lung diseases Lymphocytes Lymphocytes B Lymphocytes T Medical imaging Muscle strength Muscles Myalgia Myositis Myositis - therapy Paracetamol Patients Phenylalanine Pressure effects Receptors, Antigen, T-Cell Remission (Medicine) Rituximab Severe acute respiratory syndrome coronavirus 2 Skeletal muscle T-Lymphocytes Threonine tRNA Tyrosine
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