Structural properties and binding mechanism of DNA aptamers sensing saliva melatonin for diagnosis and monitoring of circadian clock and sleep disorders

Circadian desynchrony with the external light-dark cycle influences the rhythmic secretion of melatonin which is among the first signs of circadian rhythm sleep disorders. An accurate dim light melatonin onset (established indicator of circadian rhythm sleep disorders) measurement requires lengthy a...

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Veröffentlicht in:	Analytica chimica acta 2023-04, Vol.1251, p.340971-340971, Article 340971
Hauptverfasser:	Pundir, Meenakshi, De Rosa, Maria C., Lobanova, Liubov, Abdulmawjood, Shahad, Chen, Xiongbiao, Papagerakis, Silvana, Papagerakis, Petros
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamer Aptamers, Nucleotide - analysis Circadian Clocks Circadian Rhythm Circadian rhythm sleep disorders Circular dichroism Humans Melatonin Microscale thermophoresis Saliva - chemistry Sleep Disorders, Circadian Rhythm - diagnosis Sleep Wake Disorders
Online-Zugang:	Volltext
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