GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis

GOLM1 (Golgi membrane protein 1), a key tumor progression- and metastasis-related marker, is highly expressed in a variety of epithelium-derived human cancers. However, its expression and functions in human colorectal cancer (CRC) have been rarely explored. The present study verified the high expres...

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Veröffentlicht in:	Neoplasma 2023-02, Vol.70 (1), p.136-144
Hauptverfasser:	Mao, Zonglei, Wu, Yong, Yao, Pingan, Xing, Chungen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caco-2 Cells Cell Line, Tumor Cell Movement - genetics Cell Proliferation - physiology Colorectal Neoplasms - genetics Epithelial-Mesenchymal Transition - genetics Gene Expression Regulation, Neoplastic Glycogen Synthase Kinase 3 beta - metabolism Heterografts Humans Membrane Proteins - genetics Mice Mice, Nude Neoplasm Metastasis Proto-Oncogene Proteins c-akt - metabolism
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