Anti-Tumor Efficacy of Photodynamic Therapy of Solid Tumors in Laboratory Animals with Guanidine and Biguanidine Derivatives of Chlorine e6

We evaluated antitumor efficacy of photodynamic therapy of murine Ehrlich carcinoma and rat sarcoma M-1 with new photosensitizers 13 1 - N -(4-aminobutyl)amydo chlorine e6 ( 1 ), 13 2 -(5-guanidylbutanamido)-chlorine e6 ( 2 ), and 13 2 -(5-biguanidylbutanamido)-chlorine e6 ( 3 ). The inhibiting effe...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2023-02, Vol.174 (4), p.468-472
Hauptverfasser:	Abramova, O. B., Kozlovtseva, E. A., Drozhzhina, V. V., Ostroverkhov, P. V., Sivovolova, T. P., Arkhipova, L. M., Grin, M. A., Ivanov, S. A., Kaprin, A. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Laboratory Antitumor activity Biomedical and Life Sciences Biomedicine Cancer Carcinoma - drug therapy Care and treatment Cell Biology Chlorine Cytotoxicity Drug dosages Growth inhibition Growth rate Guanidine Guanidines Internal Medicine Laboratory animals Laboratory Medicine Lasers Medical research Mice Oncology Pathology Photochemotherapy Photodynamic therapy Photosensitizing Agents - pharmacology Photosensitizing Agents - therapeutic use Porphyrins - pharmacology Sarcoma Solid tumors Tumors
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