Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis
Abstract Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with...
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| Veröffentlicht in: | Clinical infectious diseases 2023-06, Vol.76 (12), p.2196-2199 |
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| container_end_page | 2199 |
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| container_issue | 12 |
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| container_title | Clinical infectious diseases |
| container_volume | 76 |
| creator | Heidari, Arash Sharma, Rupam Shakir, Qusai Shah, Madiha Clement, Josh Donnelley, Monica A Reynolds, Trina Trigg, Kate Jolliff, Jeff Kuran, Rasha Johnson, Royce Thompson, George R |
| description | Abstract
Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with isavuconazole, with clinical failures observed only in those with coccidioidal meningitis. |
| doi_str_mv | 10.1093/cid/ciad146 |
| format | Article |
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Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with isavuconazole, with clinical failures observed only in those with coccidioidal meningitis.</description><identifier>ISSN: 1058-4838</identifier><identifier>EISSN: 1537-6591</identifier><identifier>DOI: 10.1093/cid/ciad146</identifier><identifier>PMID: 36905151</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Antifungal Agents - therapeutic use ; Coccidioides ; Coccidioidomycosis - drug therapy ; Coccidioidomycosis - microbiology ; Humans ; Triazoles - therapeutic use</subject><ispartof>Clinical infectious diseases, 2023-06, Vol.76 (12), p.2196-2199</ispartof><rights>The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2023</rights><rights>The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c320t-e5f9da8961a16af9b55f265d4e4ed8d002fd3fb3561fa4c613c54875c19c7f373</citedby><cites>FETCH-LOGICAL-c320t-e5f9da8961a16af9b55f265d4e4ed8d002fd3fb3561fa4c613c54875c19c7f373</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1584,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36905151$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heidari, Arash</creatorcontrib><creatorcontrib>Sharma, Rupam</creatorcontrib><creatorcontrib>Shakir, Qusai</creatorcontrib><creatorcontrib>Shah, Madiha</creatorcontrib><creatorcontrib>Clement, Josh</creatorcontrib><creatorcontrib>Donnelley, Monica A</creatorcontrib><creatorcontrib>Reynolds, Trina</creatorcontrib><creatorcontrib>Trigg, Kate</creatorcontrib><creatorcontrib>Jolliff, Jeff</creatorcontrib><creatorcontrib>Kuran, Rasha</creatorcontrib><creatorcontrib>Johnson, Royce</creatorcontrib><creatorcontrib>Thompson, George R</creatorcontrib><title>Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis</title><title>Clinical infectious diseases</title><addtitle>Clin Infect Dis</addtitle><description>Abstract
Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with isavuconazole, with clinical failures observed only in those with coccidioidal meningitis.</description><subject>Antifungal Agents - therapeutic use</subject><subject>Coccidioides</subject><subject>Coccidioidomycosis - drug therapy</subject><subject>Coccidioidomycosis - microbiology</subject><subject>Humans</subject><subject>Triazoles - therapeutic use</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotlZP3mVPIshqZvOxyVFKq4WCl3pe0nzQyO6mJrtC_fVdbfXoYZhheHiHeRC6BvwAWJJH7c1QygDlJ2gMjJQ5ZxJOhxkzkVNBxAhdpPSOMYDA7ByNCJeYAYMxmi2S-ux1aNVXqG3m26zb2GwVreoa23ZZcNl0E0PrdTYPsUk_i6CHmz54E5qdDsmnS3TmVJ3s1bFP0Nt8tpq-5MvX58X0aZlrUuAut8xJo4TkoIArJ9eMuYIzQy21RhiMC2eIWxPGwSmqORDNqCiZBqlLR0oyQXeH3G0MH71NXdX4pG1dq9aGPlVFKThgSjkd0PsDqmNIKVpXbaNvVNxVgKtvb9XwQ3X0NtA3x-B-3Vjzx_6KGoDbAxD67b9Je4pQdqg</recordid><startdate>20230616</startdate><enddate>20230616</enddate><creator>Heidari, Arash</creator><creator>Sharma, Rupam</creator><creator>Shakir, Qusai</creator><creator>Shah, Madiha</creator><creator>Clement, Josh</creator><creator>Donnelley, Monica A</creator><creator>Reynolds, Trina</creator><creator>Trigg, Kate</creator><creator>Jolliff, Jeff</creator><creator>Kuran, Rasha</creator><creator>Johnson, Royce</creator><creator>Thompson, George R</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20230616</creationdate><title>Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis</title><author>Heidari, Arash ; Sharma, Rupam ; Shakir, Qusai ; Shah, Madiha ; Clement, Josh ; Donnelley, Monica A ; Reynolds, Trina ; Trigg, Kate ; Jolliff, Jeff ; Kuran, Rasha ; Johnson, Royce ; Thompson, George R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-e5f9da8961a16af9b55f265d4e4ed8d002fd3fb3561fa4c613c54875c19c7f373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antifungal Agents - therapeutic use</topic><topic>Coccidioides</topic><topic>Coccidioidomycosis - drug therapy</topic><topic>Coccidioidomycosis - microbiology</topic><topic>Humans</topic><topic>Triazoles - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Heidari, Arash</creatorcontrib><creatorcontrib>Sharma, Rupam</creatorcontrib><creatorcontrib>Shakir, Qusai</creatorcontrib><creatorcontrib>Shah, Madiha</creatorcontrib><creatorcontrib>Clement, Josh</creatorcontrib><creatorcontrib>Donnelley, Monica A</creatorcontrib><creatorcontrib>Reynolds, Trina</creatorcontrib><creatorcontrib>Trigg, Kate</creatorcontrib><creatorcontrib>Jolliff, Jeff</creatorcontrib><creatorcontrib>Kuran, Rasha</creatorcontrib><creatorcontrib>Johnson, Royce</creatorcontrib><creatorcontrib>Thompson, George R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Heidari, Arash</au><au>Sharma, Rupam</au><au>Shakir, Qusai</au><au>Shah, Madiha</au><au>Clement, Josh</au><au>Donnelley, Monica A</au><au>Reynolds, Trina</au><au>Trigg, Kate</au><au>Jolliff, Jeff</au><au>Kuran, Rasha</au><au>Johnson, Royce</au><au>Thompson, George R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis</atitle><jtitle>Clinical infectious diseases</jtitle><addtitle>Clin Infect Dis</addtitle><date>2023-06-16</date><risdate>2023</risdate><volume>76</volume><issue>12</issue><spage>2196</spage><epage>2199</epage><pages>2196-2199</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><abstract>Abstract
Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with isavuconazole, with clinical failures observed only in those with coccidioidal meningitis.</abstract><cop>US</cop><pub>Oxford University Press</pub><pmid>36905151</pmid><doi>10.1093/cid/ciad146</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1058-4838 |
| ispartof | Clinical infectious diseases, 2023-06, Vol.76 (12), p.2196-2199 |
| issn | 1058-4838 1537-6591 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Antifungal Agents - therapeutic use Coccidioides Coccidioidomycosis - drug therapy Coccidioidomycosis - microbiology Humans Triazoles - therapeutic use |
| title | Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis |
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