Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1

[Display omitted] Hepatocellular carcinoma (HCC) is one of the most common causes of malignancy-related deaths. Lenvatinib, as a multi-targeted tyrosine kinase inhibitor, has gained increasing attention for its antitumor activity. However, the effect and mechanisms of Lenvatinib on HCC metastasis ar...

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Veröffentlicht in:Biochemical pharmacology 2023-04, Vol.210, p.115489-115489, Article 115489
Hauptverfasser: Fang, Ting, Jiao, Zhen, You, Yuting, Cao, Jiahao, Wang, Chuanzheng, Liu, Jingjing, Zhao, Wenxiu
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Sprache:eng
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