SQSTM1/p62 and Hepatic Mallory-Denk Body Formation in Alcohol-Associated Liver Disease

Sequestosome 1 (SQSTM1/p62; hereafter p62) is an autophagy receptor protein for selective autophagy primarily due to its direct interaction with the microtubule light chain 3 protein that specifically localizes on autophagosome membranes. As a result, impaired autophagy leads to the accumulation of...

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Veröffentlicht in:	The American journal of pathology 2023-10, Vol.193 (10), p.1415-1426
Hauptverfasser:	Qian, Hui, Ding, Wen-Xing
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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