Testicular cytoprotective effect of glucagon like peptide-1 in diabetic rats involves inhibition of apoptosis, endoplasmic reticulum stress and activation of autophagy

This study aimed to explore the possible cytoprotective effects of exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in the testicles of diabetic rats. Exenatide has numerous advantageous properties in addition to its hypoglycemic effect. However, its impact on testicular tissue in diab...

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Veröffentlicht in:	General physiology and biophysics 2023-01, Vol.42 (2), p.135-148
Hauptverfasser:	Abdel-Hakeem, Elshymaa A, Zenhom, Nagwa M, Mokhemer, Sahar A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Autophagy Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - metabolism Endoplasmic Reticulum Stress Exenatide - pharmacology Glucagon-Like Peptide 1 - agonists Glucagon-Like Peptide 1 - metabolism Male Mammals - metabolism Rats Signal Transduction Testis - metabolism
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