Nanofiber-coated implants: Development and safety after intravitreal application in rabbits

[Display omitted] •Bevacizumab and dexamethasone can be simultaneously delivered from nanofiber-coated implants.•Nanofiber-coated implants reduced blood vessels in the CAM.•Nanofiber-coated implants are safe to the retina.•Treatment with nanofiber-coated implants can be effective for AMD. Intravitre...

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Veröffentlicht in:	International journal of pharmaceutics 2023-04, Vol.636, p.122809-122809, Article 122809
Hauptverfasser:	Guerra, Maria Carolina Andrade, Neto, Julia Teixeira, Gomes, Michele Gouvea, Dourado, Lays Fernanda Nunes, Oréfice, Rodrigo Lambert, Heneine, Luiz Guilherme Dias, Silva-Cunha, Armando, Fialho, Silvia Ligorio
Format:	Artikel
Sprache:	eng
Schlagworte:	Age-related macular degeneration Angiogenesis Inhibitors Animals Bevacizumab Dexamethasone Drug delivery Drug Implants Glucocorticoids Implant Intravitreal Intravitreal Injections Nanofiber Nanofibers Rabbits Treatment Outcome
Online-Zugang:	Volltext
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