Potential biomarkers and metabolomics of acetaminophen-induced liver injury during alcohol consumption: A preclinical investigation on C57/BL6 mice

The toxic effects of alcohol consumption on population health are significant worldwide and the synergistic toxic effects of concurrent intake of Acetaminophen and alcohol is of clinical concern. The understanding of molecular mechanisms beneath such synergism and acute toxicity may be enhanced thro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology and applied pharmacology 2023-04, Vol.465, p.116451-116451, Article 116451
Hauptverfasser:	Jaber, Malak A., Ghanim, Bayan Y., Al-Natour, Mohammad, Arqoub, Duaa Abu, Abdallah, Qasem, Abdelrazig, Salah, Alkrad, Jamal Alyousse, Kim, Dong-Hyun, Qinna, Nidal A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - toxicity Alcohol Drinking - adverse effects Amino Acids - metabolism Animals Biomarkers Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - metabolism Chemical and Drug Induced Liver Injury, Chronic - metabolism Krebs Cycle Liver Metabolism Metabolomics Mice Mice, Inbred C57BL Non-targeted LC-MS Metabolomics Oxidative Stress TCA Cycle
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!