Pteris laeta Wall. and Its New Phytochemical, Pterosinsade A, Promote Hippocampal Neurogenesis via Activating the Wnt Signaling Pathway

Pteris laeta Wall., as a traditional tea, is popular in Southwest China, but its role in preventing cognitive impairment is unclear. In this study, Pteris laeta Wall. extracts (PW) and its active compounds were evaluated for preventive effects on Alzheimer’s disease (AD) in vivo and in vitro. The re...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2023-03, Vol.71 (11), p.4586-4598
Hauptverfasser:	Shi, Yu-Sheng, Chen, Ji-Cong, Lin, Bi-Hui, Wang, Ruo-Nan, Zhao, Jie, Li, Sheng, Zhang, Yan, Zhang, Xu-Fu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - genetics Amyloid beta-Peptides - metabolism Amyloid beta-Protein Precursor - metabolism Animals Bioactive Constituents, Metabolites, and Functions Disease Models, Animal Hippocampus Mice Mice, Transgenic Neurogenesis Pteris - metabolism Wnt Signaling Pathway
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