Cancer-associated Fibroblasts in Bladder Cancer: Origin, Biology, and Therapeutic Opportunities

Cancer-associated fibroblasts are a major component of the tumour microenvironment. The clinical and molecular heterogeneity of bladder cancer is reflected in the microenvironment. This review emphasises these aspects and the need to acquire further knowledge on the role of cancer-associated fibrobl...

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Veröffentlicht in:	European urology oncology 2023-08, Vol.6 (4), p.366-375
Hauptverfasser:	Caramelo, Belén, Zagorac, Sladjana, Corral, Sonia, Marqués, Miriam, Real, Francisco X.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Bladder cancer Cancer-Associated Fibroblasts Carcinoma, Transitional Cell Chemotherapy Fibroblasts Humans Immune checkpoint inhibitors Immunotherapy Male Molecular subtypes Signatures Single-cell RNA-seq Tumor Microenvironment Tumour microenvironment Urinary Bladder Urinary Bladder Neoplasms - therapy Urothelial carcinoma
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