ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11

Abnormal spindle‐like microcephaly‐associated (ASPM) protein is crucial to the mitotic spindle function during cell replication and tumor progression in multiple tumor types. However, the effect of ASPM in anaplastic thyroid carcinoma (ATC) has not yet been understood. The present study is to elucid...

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Veröffentlicht in:	Cell biology international 2023-07, Vol.47 (7), p.1209-1221
Hauptverfasser:	Fang, Qilu, Li, Qinglin, Qi, Yajun, Pan, Zongfu, Feng, Tingting, Xin, Wenxiu
Format:	Artikel
Sprache:	eng
Schlagworte:	anaplastic thyroid carcinoma Animals ASPM Cell Line, Tumor Cell Movement Cell Proliferation Humans invasion KIF11 Kinesins - genetics Mice Mice, Knockout Mice, Nude migration Nerve Tissue Proteins Therapeutic targets Thyroid cancer Thyroid carcinoma Thyroid Carcinoma, Anaplastic - genetics Thyroid Carcinoma, Anaplastic - metabolism Thyroid Carcinoma, Anaplastic - pathology Thyroid Neoplasms - metabolism Tumorigenesis Ubiquitin Ubiquitins - pharmacology Vimentin
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