Development and preliminary validation of a modified EUCAST yeast broth microdilution MIC method with Tween 20-supplemented medium for rezafungin

Abstract Background Rezafungin is a novel, once-weekly echinocandin. EUCAST rezafungin MIC testing has been associated with a good separation of WT and target gene mutant isolates in single-centre studies, but an unacceptable inter-laboratory MIC variation has prevented EUCAST breakpoint setting. Th...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2023-04, Vol.78 (4), p.1102-1110
Hauptverfasser:	Zuill, Douglas E, Almaguer, Amanda L, Donatelli, Joanna, Arendrup, Maiken Cavling, Locke, Jeffrey B
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - pharmacology Candida Dietary Supplements Echinocandins - pharmacology Microbial Sensitivity Tests Polysorbates - pharmacology Saccharomyces cerevisiae
Online-Zugang:	Volltext
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