Water Maintains the UV–Vis Spectral Features During the Insertion of Anionic Naproxen and Ibuprofen into Model Cell Membranes

UV–vis spectra of anionic ibuprofen and naproxen in a model lipid bilayer of the cell membrane are investigated using computational techniques in combination with a comparative analysis of drug spectra in purely aqueous environments. The simulations aim at elucidating the intricacies behind the negl...

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Veröffentlicht in:	The journal of physical chemistry. B 2023-03, Vol.127 (10), p.2146-2155
Hauptverfasser:	Rojas-Valencia, Natalia, Gómez, Sara, Giovannini, Tommaso, Cappelli, Chiara, Restrepo, Albeiro, Núñez−Zarur, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	B: Biophysical and Biochemical Systems and Processes Cell Membrane Ibuprofen Lipids Naproxen Quantum Theory Water - chemistry
Online-Zugang:	Volltext
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