Development, initial validation, and application of a visual read method for 18FMK-6240 tau PET

The positron emission tomography (PET) radiotracer [18F]MK-6240 exhibits high specificity for neurofibrillary tangles (NFTs) of tau protein in Alzheimer's disease (AD), high sensitivity to medial temporal and neocortical NFTs, and low within-brain background. Objectives were to develop and vali...

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Veröffentlicht in:Alzheimer's & dementia : translational research & clinical interventions 2023-01, Vol.9 (1), p.e12372
Hauptverfasser: Shuping, Joanna L, Matthews, Dawn C, Adamczuk, Katarzyna, Scott, David, Rowe, Christopher C, Kreisl, William C, Johnson, Sterling C, Lukic, Ana S, Johnson, Keith A, Rosa-Neto, Pedro, Andrews, Randolph D, Van Laere, Koen, Cordes, Lindsay, Ward, Larry, Wilde, Claire L, Barakos, Jerome, Purcell, Derk D, Devanand, Davangere P, Stern, Yaakov, Luchsinger, Jose A, Sur, Cyrille, Price, Julie C, Brickman, Adam M, Klunk, William E, Boxer, Adam L, Mathotaarachchi, Sulantha S, Lao, Patrick J, Evelhoch, Jeffrey L
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Sprache:eng
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