An anticoagulant/procoagulant self-converting and bleeding site–targeting systemic nanotherapy for rapidly controlling noncompressible bleeding without risk of thrombosis

Hemorrhage, in particular noncompressible hemorrhage, is the leading cause of casualties in combat trauma and civilian trauma. Although systemic agents can stop bleeding at both inaccessible and accessible injury sites, the application of systemic hemostats in clinics is strictly limited by the nont...

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