Slow skeletal muscle troponin T acts as a potential prognostic biomarker and therapeutic target for hepatocellular carcinoma

[Display omitted] •TNNT1 was upregulated in HCC tissues compared with the adjacent non-tumoral liver.•Serum TNNT1 was upregulated in HCC patients compared with healthy donors.•TNNT1 may serve as a potential prognostic and diagnostic biomarker for HCC.•Anti-TNNT1 inhibited oncogenic behaviors and EMT...

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Veröffentlicht in:	Gene 2023-05, Vol.865, p.147331-147331, Article 147331
Hauptverfasser:	Huang, Shih-Chung, Huang, Chao-Cheng, Ko, Chou-Yuan, Huang, Cheng-Yi, Liu, Ching-Han, Lee, Yung-Kuo, Chen, Tung-Yuan, Hsueh, Chao-Wen, Tzou, Shiow-Jyu, Tai, Ming-Hong, Hu, Tsung-Hui, Tsai, Ming-Chao, Lee, Wen-Chin, Ho, Yu-Cheng, Wu, Cheng-Chun, Chang, Yi-Chen, Chang, Jung-Jui, Liu, Kai-Hsi, Li, Chiao-Ching, Wen, Zhi-Hong, Chang, Chen-Lin, Chu, Tian-Huei
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-TNNT1 Biomarker Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Cell Line, Tumor Cell Movement - genetics Epithelial-Mesenchymal Transition - genetics Epithelial–mesenchymal transition Gene Expression Regulation, Neoplastic Hepatocellular carcinoma Humans Liver Neoplasms - pathology Muscle, Skeletal - metabolism Prognosis Slow skeletal muscle troponin T Troponin T - genetics
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