Cancer-targeted fucoidan‑iron oxide nanoparticles for synergistic chemotherapy/chemodynamic theranostics through amplification of P-selectin and oxidative stress

A combination of chemotherapy and chemodynamic therapy (CDT) is being developed to improve the theranostic efficacy and biological safety of current therapies. However, most CDT agents are restricted due to complex issues such as multiple components, low colloidal stability, carrier-associated toxic...

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Veröffentlicht in:	International journal of biological macromolecules 2023-04, Vol.235, p.123821-123821, Article 123821
Hauptverfasser:	Ho, Thi-Luu, Mutalik, Chinmaya, Rethi, Lekshmi, Nguyen, Huynh-Ngoc Truc, Jheng, Pei-Ru, Wong, Chin-Chean, Yang, Tzu-Sen, Nguyen, Thi Thuy, Mansel, Bradley W., Wang, Chen-An, Chuang, Er-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification of P-selectin and oxidative stress Cancer-targeted fucoidan‑iron oxide nanoparticles Cell Line, Tumor Humans Lung Neoplasms - drug therapy Magnetic Iron Oxide Nanoparticles Nanoparticles - therapeutic use Neoplasms - drug therapy Oxidative Stress P-Selectin Precision Medicine Synergistic chemotherapy/chemodynamic theranostics Theranostic Nanomedicine
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