Melatonin modulates the Warburg effect and alters the morphology of hepatocellular carcinoma cell line resulting in reduced viability and migratory potential

Hepatocellular Carcinoma (HCC) is a primary neoplasm derived from hepatocytes with low responsiveness and recurrent chemoresistance. Melatonin is an alternative agent that may be helpful in treating HCC. We aimed to study in HuH 7.5 cells whether melatonin treatment exerts antitumor effects and, if...

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Veröffentlicht in:	Life sciences (1973) 2023-04, Vol.319, p.121530-121530, Article 121530
Hauptverfasser:	Cruz, Ellen Mayara Souza, Concato, Virginia Marcia, de Morais, Juliana Maria Bitencourt, Silva, Taylon Felipe, Inoue, Fabricio Seidy Ribeiro, de Souza Cremer, Milena, Bidóia, Danielle Lazarin, Machado, Rayanne Regina Beltrame, de Almeida Chuffa, Luiz Gustavo, Mantovani, Mário Sérgio, Panis, Carolina, Pavanelli, Wander Rogério, Seiva, Fábio Rodrigues Ferreira
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant therapy Carcinoma, Hepatocellular - pathology Cell Line, Tumor HuH 7.5 cell Humans Lactates Liver cancer Liver Neoplasms - pathology Melatonin - pharmacology Melatonin - therapeutic use Warburg effect
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