PD-L1 Enhanced by cis-Urocanic Acid on Langerhans Cells Inhibits Vγ4+ γδT17 Cells in Imiquimod-Induced Skin Inflammation

Psoriasis is an IL-23/IL-17-mediated inflammatory autoimmune dermatosis, and UVB may contribute to immunosuppression and ameliorate associated symptoms. One of the pathophysiology underlying UVB therapy is the production of cis-urocanic acid (cis-UCA) by keratinocytes. However, the detailed mechanis...

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Veröffentlicht in:	Journal of investigative dermatology 2023-08, Vol.143 (8), p.1449-1460
Hauptverfasser:	Yeh, Chen-Yun, Su, Sheng-Han, Tan, Yeh Fong, Tsai, Tsen-Fang, Liang, Pi-Hui, Kelel, Musin, Weng, Hao-Jui, Hsiao, Yu-Ping, Lu, Chun-Hao, Tsai, Ching-Hui, Lee, Chih-Hung, Clausen, Björn E., Liu, Fu-Tong, Lee, Yungling Leo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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