Trifluoromethyl Vinamidinium Salt as a Promising Precursor for Fused β‑Trifluoromethyl Pyridines

An efficient chlorotrimethylsilane-promoted synthetic protocol for the preparation of functionalized fused β-trifluoromethyl pyridines by cyclization of electron-rich aminoheterocycles or substituted anilines with a trifluoromethyl vinamidinium salt was developed. The efficient and scalable approach...

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Veröffentlicht in:	Journal of organic chemistry 2023-03, Vol.88 (5), p.2961-2972
Hauptverfasser:	Mityuk, Andrii P., Kiriakov, Oleksandr M., Tiutiunnyk, Vladislav V., Lebed, Pavlo S., Grabchuk, Galyna P., Rusanov, Eduard B., Volochnyuk, Dmitriy M., Ryabukhin, Sergey V.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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