On minimal focal distance of a focused ultrasound probe for neuromodulation

On minimal focal distance of a focused ultrasound probe for neuromodulation

Focal distance is a key parameter for a focused ultrasound probe, especially in mouse brain stimulation where targets are right below the skull. A closed-form solution for the minimal focal distance with a given transducer size was derived in this study to facilitate precise focal spot alignment wit...

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Veröffentlicht in:JASA express letters 2023-02, Vol.3 (2), p.024002-024002
Hauptverfasser: Chu, Ya-Cherng, Ho, Chien-Ying, Chuo, Yue, Wu, Hao-Hsuan, Wang, Jaw-Lin
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creator Chu, Ya-Cherng
Ho, Chien-Ying
Chuo, Yue
Wu, Hao-Hsuan
Wang, Jaw-Lin
description Focal distance is a key parameter for a focused ultrasound probe, especially in mouse brain stimulation where targets are right below the skull. A closed-form solution for the minimal focal distance with a given transducer size was derived in this study to facilitate precise focal spot alignment with targets in the mouse brain. The spherical profile corresponding to the minimal focal distance does not produce accurate focusing. An iterative algorithm based on Snell's law was introduced for lens profile calculation. With a suitable step size, an accurate lens profile can be obtained for the minimal focal distance.
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title On minimal focal distance of a focused ultrasound probe for neuromodulation
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