Quantitative Consideration of Clinical Increases in Serum Creatinine Caused by Renal Transporter Inhibition

Creatinine is a common biomarker of renal function and is secreted in the renal tubular cells via drug transporters such as organic cation transporter 2 and multidrug and toxin extrusion (MATE) 1/2-K. To differentiate between drug-induced acute kidney injury (AKI) and drug interactions through the r...

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Veröffentlicht in:	Drug metabolism and disposition 2023-09, Vol.51 (9), p.1114-1126
Hauptverfasser:	Nakada, Tomohisa, Kudo, Toshiyuki, Ito, Kiyomi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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