The protective impact of hesperidin against carbimazole-induced hypothyroidism, via enhancement of inflammatory cytokines, histopathological alterations, and Nrf2/HO-1

The aim of this study was to evaluate the anti-inflammatory, antioxidant, and antiproliferative effects of hesperidin (HSP) and eltroxin (ELT) on hypothyroidism (HPO) induced by carbimazole (CBZ) in white male albino rats. Thirty-two adult rats were categorized into four groups: Group 1, no treatmen...

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Veröffentlicht in:	Environmental science and pollution research international 2023-04, Vol.30 (18), p.53589-53604
Hauptverfasser:	Hegazy, Walaa, Abdul-Hamid, Manal, Abdel-Rehiem, Eman S., Abdel-Moneim, Adel, Salah, Marwa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Antigens Antioxidants Antioxidants - pharmacology Antiproliferatives Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Carbimazole - pharmacology Cyclooxygenase-2 Cytokines Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Health Environmental science Heme Hesperidin Hesperidin - pharmacology Hormones Hypothyroidism Hypothyroidism - chemically induced Immunohistochemistry Inflammation Interleukin 17 Interleukins Lipid peroxidation Lipids Male NF-E2-Related Factor 2 - metabolism NF-kappa B - metabolism Nitric oxide Nitric-oxide synthase Oxidative Stress Oxygenase Peroxidation Proliferating cell nuclear antigen Rats Reagents Research Article Thyroglobulin Thyroid Thyroid gland Thyroid hormones Thyroid-stimulating hormone Waste Water Technology Water Management Water Pollution Control
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