Combined Reverse-Transcriptase Multiplex Ligation-Dependent Probe Amplification and Next-Generation Sequencing Analyses to Assign Unclassified BCL2−/BCL6− Nonrearranged Small B-Cell Lymphoid Neoplasms as Follicular or Nodal Marginal Zone Lymphoma

Distinguishing between follicular lymphoma (FL) and nodal marginal zone lymphoma (NMZL) can be difficult when morphologic and phenotypic features are unusual and characteristic cytogenetic rearrangements are absent. We evaluated the diagnostic contribution of ancillary techniques—including fluoresce...

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Veröffentlicht in:	Modern pathology 2023-02, Vol.36 (2), p.100043-100043, Article 100043
Hauptverfasser:	Sesboue, Come, Galtier, Jean, Jeanneau, Marie, Chauvel, Annick, Laharanne, Elodie, Amintas, Samuel, Merlio, Jean-Philippe, Bouabdallah, Krimo, Gros, François-Xavier, de Leval, Laurence, Gros, Audrey, Parrens, Marie
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Deletion DNA-Directed RNA Polymerases FISH High-Throughput Nucleotide Sequencing Humans In Situ Hybridization, Fluorescence Lymphoma, B-Cell, Marginal Zone - genetics Lymphoma, Follicular - diagnosis Lymphoma, Follicular - genetics Multiplex Polymerase Chain Reaction NGS Proto-Oncogene Proteins c-bcl-2 Proto-Oncogene Proteins c-bcl-6 RT-MLPA Small B-cell lymphoid neoplasm
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