In silico-chemogenomic repurposing of new chemical scaffolds for histoplasmosis treatment

Histoplasmosis is a systemic form of endemic mycosis to the American continent and may be lethal to people living with HIV/AIDS. The drugs available for treating histoplasmosis are limited, costly, and highly toxic. New drug development is time-consuming and costly; hence, drug repositioning is an a...

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Veröffentlicht in:	Journal de mycologie médicale 2023-05, Vol.33 (2), p.101363-101363, Article 101363
Hauptverfasser:	Santos, Andressa Santana, Borges dos Anjos, Laura Raniere, Costa, Vinícius Alexandre Fiaia, Freitas, Vivianny Aparecida Queiroz, Zara, Ana Laura de Sene Amâncio, Costa, Carolina Rodrigues, Neves, Bruno Junior, Silva, Maria do Rosário Rodrigues
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS-Related Opportunistic Infections - microbiology Antifungal agent Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Drug Repositioning Histoplasma - genetics Histoplasmosis Histoplasmosis - epidemiology Humans Molecular Docking Simulation
Online-Zugang:	Volltext
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