Desaturation of sebaceous‐type saturated fatty acids through the SCD1 and the FADS2 pathways impacts lipid neosynthesis and inflammatory response in sebocytes in culture

Sebum is a lipid‐rich mixture secreted by the sebaceous gland (SG) onto the skin surface. By penetrating through the epidermis, sebum may be involved in the regulation of epidermal and dermal cells in both healthy and diseased skin conditions. Saturated and monounsaturated fatty acids (FAs), found a...

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Veröffentlicht in:Experimental dermatology 2023-06, Vol.32 (6), p.808-821
Hauptverfasser: Flori, Enrica, Mastrofrancesco, Arianna, Ottaviani, Monica, Maiellaro, Miriam, Zouboulis, Christos C., Camera, Emanuela
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Sprache:eng
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