Biocompatibility and biofouling of MEMS drug delivery devices

The biocompatibility and biofouling of the microfabrication materials for a MEMS drug delivery device have been evaluated. The in vivo inflammatory and wound healing response of MEMS drug delivery component materials, metallic gold, silicon nitride, silicon dioxide, silicon, and SU-8 TM photoresist,...

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Veröffentlicht in:	Biomaterials 2003-05, Vol.24 (11), p.1959-1967
Hauptverfasser:	Voskerician, Gabriela, Shive, Matthew S., Shawgo, Rebecca S., Recum, Horst von, Anderson, James M., Cima, Michael J., Langer, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Back Biocompatibility Biocompatible Materials - adverse effects Biofouling Cell Adhesion Drug Delivery Systems - adverse effects Drug Delivery Systems - instrumentation Drug Delivery Systems - methods Drug Implants - adverse effects Electronics Exudate analysis Exudates and Transudates - immunology Exudates and Transudates - metabolism Female Foreign-Body Reaction - diagnosis Foreign-Body Reaction - etiology Leukocyte Count Material surface analysis Materials Testing - methods MEMS component materials Miniaturization Muscles Myositis - diagnosis Myositis - etiology Rats Rats, Sprague-Dawley Surface Properties
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