Redox-responsive paclitaxel-pentadecanoic acid conjugate encapsulated human serum albumin nanoparticles for cancer therapy

Preparation procedure, endocytosis process and release mechanism of human serum albumin (HSA)/disulfide bond bridged paclitaxel-pentadecanoic acid conjugate (PTX-SS-C10-COOH) nanoparticles (HPTX NPs). [Display omitted] Human serum albumin (HSA) is an important nanocarrier of hydrophobic drugs due to...

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Veröffentlicht in:	International journal of pharmaceutics 2023-03, Vol.635, p.122761-122761, Article 122761
Hauptverfasser:	Zhang, Yanhao, Wang, Ji, Xing, Hanlei, Liu, Chao, Li, Xinsong
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumin Antitumor activity Cell Line, Tumor Disulfides Humans Nanoparticle Nanoparticles - chemistry Neoplasms - drug therapy Oxidation-Reduction Paclitaxel Paclitaxel prodrug Redox sensitivity Serum Albumin, Human
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