Expression of the Ovine Gene and the Relationship Between Its Polymorphism and Feed Efficiency Traits
In the mutton industry, feed efficiency traits have the greatest influence on the economic benefits of sheep raised in housing conditions. In this study, quantitative real-time PCR (qRT-PCR), Sanger sequencing, and KASPar methods were used to detect the expression levels of the B cell scaffold prote...
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| Veröffentlicht in: | DNA and cell biology 2023-04, Vol.42 (4), p.194-202 |
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| creator | Zeng, Xiwen Wang, Weimin Zhang, Deyin Li, Xiaolong Zhang, Yukun Zhao, Yuan Zhao, Liming Wang, Jianghui Xu, Dan Cheng, Jiangbo Li, Wenxin Zhou, Bubo Lin, Changchun Yang, Xiaobin Zhai, Rui Ma, Zongwu Liu, Jia Cui, Panpan Weng, Xiuxiu Wu, Weiwei Zhang, Xiaoxue Zheng, Wenxin |
| description | In the mutton industry, feed efficiency traits have the greatest influence on the economic benefits of sheep raised in housing conditions. In this study, quantitative real-time PCR (qRT-PCR), Sanger sequencing, and KASPar methods were used to detect the expression levels of the B cell scaffold protein with ankyrin repeats 1 (
BANK1
) gene and the relationship between its polymorphism and feed efficiency traits in Hu sheep. The qRT-PCR results showed that the
BANK1
gene was extensively expressed in 10 tissues and it was expressed at remarkably higher levels in lymph than in other tissues (
p
T, was detected in intron 4 of the
BANK1
gene and proved to be remarkably associated with feed efficiency traits (
p
|
| doi_str_mv | 10.1089/dna.2022.0529 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2780068624</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2796551058</sourcerecordid><originalsourceid>FETCH-LOGICAL-c365t-36e6ef30ebba0821e3365dbeae61e400a819c67971fbc593ebaa5054bfdc2f093</originalsourceid><addsrcrecordid>eNqF0EtLxDAUBeAgiu-lWwm4cdPxJmnSdqkyPkAYEV2XtL1hIm1ak446_96MM7pw4yYJh49DOIScMJgwyIuLxukJB84nIHmxRfaZlFmSpQK24xvSNJFpke-RgxBeAaJhsEv2hMp5NNk-wenn4DEE2zvaGzrOkc7erUN6i_HQrvmOnrDVYyRhbgd6heMHoqP3Y6CPfbvsej_Mbei-9Q1iQ6fG2Nqiq5f02Ws7hiOyY3Qb8HhzH5KXm-nz9V3yMLu9v758SGqh5JgIhQqNAKwqDTlnKGLcVKhRMUwBdM6KWmVFxkxVy0JgpbUEmVamqbmBQhyS83Xv4Pu3BYax7GyosW21w34RSp7lACpXPI307A997Rfexd9FVSgpGcg8qmStat-H4NGUg7ed9suSQbnav4z7l6v9y9X-0Z9uWhdVh82v_hk8ArEGq1g711qs0I__1H4B2rCR3Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2796551058</pqid></control><display><type>article</type><title>Expression of the Ovine Gene and the Relationship Between Its Polymorphism and Feed Efficiency Traits</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Zeng, Xiwen ; Wang, Weimin ; Zhang, Deyin ; Li, Xiaolong ; Zhang, Yukun ; Zhao, Yuan ; Zhao, Liming ; Wang, Jianghui ; Xu, Dan ; Cheng, Jiangbo ; Li, Wenxin ; Zhou, Bubo ; Lin, Changchun ; Yang, Xiaobin ; Zhai, Rui ; Ma, Zongwu ; Liu, Jia ; Cui, Panpan ; Weng, Xiuxiu ; Wu, Weiwei ; Zhang, Xiaoxue ; Zheng, Wenxin</creator><creatorcontrib>Zeng, Xiwen ; Wang, Weimin ; Zhang, Deyin ; Li, Xiaolong ; Zhang, Yukun ; Zhao, Yuan ; Zhao, Liming ; Wang, Jianghui ; Xu, Dan ; Cheng, Jiangbo ; Li, Wenxin ; Zhou, Bubo ; Lin, Changchun ; Yang, Xiaobin ; Zhai, Rui ; Ma, Zongwu ; Liu, Jia ; Cui, Panpan ; Weng, Xiuxiu ; Wu, Weiwei ; Zhang, Xiaoxue ; Zheng, Wenxin</creatorcontrib><description>In the mutton industry, feed efficiency traits have the greatest influence on the economic benefits of sheep raised in housing conditions. In this study, quantitative real-time PCR (qRT-PCR), Sanger sequencing, and KASPar methods were used to detect the expression levels of the B cell scaffold protein with ankyrin repeats 1 (
BANK1
) gene and the relationship between its polymorphism and feed efficiency traits in Hu sheep. The qRT-PCR results showed that the
BANK1
gene was extensively expressed in 10 tissues and it was expressed at remarkably higher levels in lymph than in other tissues (
p
< 0.05). Then, the polymorphism locus, g.93888 A > T, was detected in intron 4 of the
BANK1
gene and proved to be remarkably associated with feed efficiency traits (
p
< 0.05). Hence, the
BANK1
gene can be used as a candidate gene for improving the feed efficiency of Hu sheep and this locus could be used as a potential molecular marker for breeding high-feed efficiency sheep in future breeding efforts.</description><identifier>ISSN: 1044-5498</identifier><identifier>EISSN: 1557-7430</identifier><identifier>DOI: 10.1089/dna.2022.0529</identifier><identifier>PMID: 36827437</identifier><language>eng</language><publisher>United States: Mary Ann Liebert, Inc., publishers</publisher><subject>Animal husbandry ; Animals ; Ankyrins ; Breeding ; Efficiency ; Feed efficiency ; Gene expression ; Introns ; Mutton ; Phenotype ; Physical growth ; Polymorphism ; Polymorphism, Single Nucleotide ; Sheep ; Sheep - genetics</subject><ispartof>DNA and cell biology, 2023-04, Vol.42 (4), p.194-202</ispartof><rights>2023, Mary Ann Liebert, Inc., publishers</rights><rights>Copyright Mary Ann Liebert, Inc. Apr 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-36e6ef30ebba0821e3365dbeae61e400a819c67971fbc593ebaa5054bfdc2f093</citedby><cites>FETCH-LOGICAL-c365t-36e6ef30ebba0821e3365dbeae61e400a819c67971fbc593ebaa5054bfdc2f093</cites><orcidid>0000-0002-3289-5393</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36827437$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zeng, Xiwen</creatorcontrib><creatorcontrib>Wang, Weimin</creatorcontrib><creatorcontrib>Zhang, Deyin</creatorcontrib><creatorcontrib>Li, Xiaolong</creatorcontrib><creatorcontrib>Zhang, Yukun</creatorcontrib><creatorcontrib>Zhao, Yuan</creatorcontrib><creatorcontrib>Zhao, Liming</creatorcontrib><creatorcontrib>Wang, Jianghui</creatorcontrib><creatorcontrib>Xu, Dan</creatorcontrib><creatorcontrib>Cheng, Jiangbo</creatorcontrib><creatorcontrib>Li, Wenxin</creatorcontrib><creatorcontrib>Zhou, Bubo</creatorcontrib><creatorcontrib>Lin, Changchun</creatorcontrib><creatorcontrib>Yang, Xiaobin</creatorcontrib><creatorcontrib>Zhai, Rui</creatorcontrib><creatorcontrib>Ma, Zongwu</creatorcontrib><creatorcontrib>Liu, Jia</creatorcontrib><creatorcontrib>Cui, Panpan</creatorcontrib><creatorcontrib>Weng, Xiuxiu</creatorcontrib><creatorcontrib>Wu, Weiwei</creatorcontrib><creatorcontrib>Zhang, Xiaoxue</creatorcontrib><creatorcontrib>Zheng, Wenxin</creatorcontrib><title>Expression of the Ovine Gene and the Relationship Between Its Polymorphism and Feed Efficiency Traits</title><title>DNA and cell biology</title><addtitle>DNA Cell Biol</addtitle><description>In the mutton industry, feed efficiency traits have the greatest influence on the economic benefits of sheep raised in housing conditions. In this study, quantitative real-time PCR (qRT-PCR), Sanger sequencing, and KASPar methods were used to detect the expression levels of the B cell scaffold protein with ankyrin repeats 1 (
BANK1
) gene and the relationship between its polymorphism and feed efficiency traits in Hu sheep. The qRT-PCR results showed that the
BANK1
gene was extensively expressed in 10 tissues and it was expressed at remarkably higher levels in lymph than in other tissues (
p
< 0.05). Then, the polymorphism locus, g.93888 A > T, was detected in intron 4 of the
BANK1
gene and proved to be remarkably associated with feed efficiency traits (
p
< 0.05). Hence, the
BANK1
gene can be used as a candidate gene for improving the feed efficiency of Hu sheep and this locus could be used as a potential molecular marker for breeding high-feed efficiency sheep in future breeding efforts.</description><subject>Animal husbandry</subject><subject>Animals</subject><subject>Ankyrins</subject><subject>Breeding</subject><subject>Efficiency</subject><subject>Feed efficiency</subject><subject>Gene expression</subject><subject>Introns</subject><subject>Mutton</subject><subject>Phenotype</subject><subject>Physical growth</subject><subject>Polymorphism</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Sheep</subject><subject>Sheep - genetics</subject><issn>1044-5498</issn><issn>1557-7430</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0EtLxDAUBeAgiu-lWwm4cdPxJmnSdqkyPkAYEV2XtL1hIm1ak446_96MM7pw4yYJh49DOIScMJgwyIuLxukJB84nIHmxRfaZlFmSpQK24xvSNJFpke-RgxBeAaJhsEv2hMp5NNk-wenn4DEE2zvaGzrOkc7erUN6i_HQrvmOnrDVYyRhbgd6heMHoqP3Y6CPfbvsej_Mbei-9Q1iQ6fG2Nqiq5f02Ws7hiOyY3Qb8HhzH5KXm-nz9V3yMLu9v758SGqh5JgIhQqNAKwqDTlnKGLcVKhRMUwBdM6KWmVFxkxVy0JgpbUEmVamqbmBQhyS83Xv4Pu3BYax7GyosW21w34RSp7lACpXPI307A997Rfexd9FVSgpGcg8qmStat-H4NGUg7ed9suSQbnav4z7l6v9y9X-0Z9uWhdVh82v_hk8ArEGq1g711qs0I__1H4B2rCR3Q</recordid><startdate>20230401</startdate><enddate>20230401</enddate><creator>Zeng, Xiwen</creator><creator>Wang, Weimin</creator><creator>Zhang, Deyin</creator><creator>Li, Xiaolong</creator><creator>Zhang, Yukun</creator><creator>Zhao, Yuan</creator><creator>Zhao, Liming</creator><creator>Wang, Jianghui</creator><creator>Xu, Dan</creator><creator>Cheng, Jiangbo</creator><creator>Li, Wenxin</creator><creator>Zhou, Bubo</creator><creator>Lin, Changchun</creator><creator>Yang, Xiaobin</creator><creator>Zhai, Rui</creator><creator>Ma, Zongwu</creator><creator>Liu, Jia</creator><creator>Cui, Panpan</creator><creator>Weng, Xiuxiu</creator><creator>Wu, Weiwei</creator><creator>Zhang, Xiaoxue</creator><creator>Zheng, Wenxin</creator><general>Mary Ann Liebert, Inc., publishers</general><general>Mary Ann Liebert, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3289-5393</orcidid></search><sort><creationdate>20230401</creationdate><title>Expression of the Ovine Gene and the Relationship Between Its Polymorphism and Feed Efficiency Traits</title><author>Zeng, Xiwen ; Wang, Weimin ; Zhang, Deyin ; Li, Xiaolong ; Zhang, Yukun ; Zhao, Yuan ; Zhao, Liming ; Wang, Jianghui ; Xu, Dan ; Cheng, Jiangbo ; Li, Wenxin ; Zhou, Bubo ; Lin, Changchun ; Yang, Xiaobin ; Zhai, Rui ; Ma, Zongwu ; Liu, Jia ; Cui, Panpan ; Weng, Xiuxiu ; Wu, Weiwei ; Zhang, Xiaoxue ; Zheng, Wenxin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-36e6ef30ebba0821e3365dbeae61e400a819c67971fbc593ebaa5054bfdc2f093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Animal husbandry</topic><topic>Animals</topic><topic>Ankyrins</topic><topic>Breeding</topic><topic>Efficiency</topic><topic>Feed efficiency</topic><topic>Gene expression</topic><topic>Introns</topic><topic>Mutton</topic><topic>Phenotype</topic><topic>Physical growth</topic><topic>Polymorphism</topic><topic>Polymorphism, Single Nucleotide</topic><topic>Sheep</topic><topic>Sheep - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zeng, Xiwen</creatorcontrib><creatorcontrib>Wang, Weimin</creatorcontrib><creatorcontrib>Zhang, Deyin</creatorcontrib><creatorcontrib>Li, Xiaolong</creatorcontrib><creatorcontrib>Zhang, Yukun</creatorcontrib><creatorcontrib>Zhao, Yuan</creatorcontrib><creatorcontrib>Zhao, Liming</creatorcontrib><creatorcontrib>Wang, Jianghui</creatorcontrib><creatorcontrib>Xu, Dan</creatorcontrib><creatorcontrib>Cheng, Jiangbo</creatorcontrib><creatorcontrib>Li, Wenxin</creatorcontrib><creatorcontrib>Zhou, Bubo</creatorcontrib><creatorcontrib>Lin, Changchun</creatorcontrib><creatorcontrib>Yang, Xiaobin</creatorcontrib><creatorcontrib>Zhai, Rui</creatorcontrib><creatorcontrib>Ma, Zongwu</creatorcontrib><creatorcontrib>Liu, Jia</creatorcontrib><creatorcontrib>Cui, Panpan</creatorcontrib><creatorcontrib>Weng, Xiuxiu</creatorcontrib><creatorcontrib>Wu, Weiwei</creatorcontrib><creatorcontrib>Zhang, Xiaoxue</creatorcontrib><creatorcontrib>Zheng, Wenxin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>DNA and cell biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zeng, Xiwen</au><au>Wang, Weimin</au><au>Zhang, Deyin</au><au>Li, Xiaolong</au><au>Zhang, Yukun</au><au>Zhao, Yuan</au><au>Zhao, Liming</au><au>Wang, Jianghui</au><au>Xu, Dan</au><au>Cheng, Jiangbo</au><au>Li, Wenxin</au><au>Zhou, Bubo</au><au>Lin, Changchun</au><au>Yang, Xiaobin</au><au>Zhai, Rui</au><au>Ma, Zongwu</au><au>Liu, Jia</au><au>Cui, Panpan</au><au>Weng, Xiuxiu</au><au>Wu, Weiwei</au><au>Zhang, Xiaoxue</au><au>Zheng, Wenxin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Expression of the Ovine Gene and the Relationship Between Its Polymorphism and Feed Efficiency Traits</atitle><jtitle>DNA and cell biology</jtitle><addtitle>DNA Cell Biol</addtitle><date>2023-04-01</date><risdate>2023</risdate><volume>42</volume><issue>4</issue><spage>194</spage><epage>202</epage><pages>194-202</pages><issn>1044-5498</issn><eissn>1557-7430</eissn><abstract>In the mutton industry, feed efficiency traits have the greatest influence on the economic benefits of sheep raised in housing conditions. In this study, quantitative real-time PCR (qRT-PCR), Sanger sequencing, and KASPar methods were used to detect the expression levels of the B cell scaffold protein with ankyrin repeats 1 (
BANK1
) gene and the relationship between its polymorphism and feed efficiency traits in Hu sheep. The qRT-PCR results showed that the
BANK1
gene was extensively expressed in 10 tissues and it was expressed at remarkably higher levels in lymph than in other tissues (
p
< 0.05). Then, the polymorphism locus, g.93888 A > T, was detected in intron 4 of the
BANK1
gene and proved to be remarkably associated with feed efficiency traits (
p
< 0.05). Hence, the
BANK1
gene can be used as a candidate gene for improving the feed efficiency of Hu sheep and this locus could be used as a potential molecular marker for breeding high-feed efficiency sheep in future breeding efforts.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc., publishers</pub><pmid>36827437</pmid><doi>10.1089/dna.2022.0529</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-3289-5393</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1044-5498 |
| ispartof | DNA and cell biology, 2023-04, Vol.42 (4), p.194-202 |
| issn | 1044-5498 1557-7430 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2780068624 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animal husbandry Animals Ankyrins Breeding Efficiency Feed efficiency Gene expression Introns Mutton Phenotype Physical growth Polymorphism Polymorphism, Single Nucleotide Sheep Sheep - genetics |
| title | Expression of the Ovine Gene and the Relationship Between Its Polymorphism and Feed Efficiency Traits |
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