Indirect co‐culture of islet cells in 3D biocompatible collagen/laminin scaffold with angiomiRs transfected mesenchymal stem cells

Diabetes is an autoimmune disease in which the pancreatic islets produce insufficient insulin. One of the treatment strategies is islet isolation, which may damage these cells as they lack vasculature. Biocompatible scaffolds are one of the efficient techniques for dealing with this issue. The curre...

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Veröffentlicht in:	Cell biochemistry and function 2023-04, Vol.41 (3), p.296-308
Hauptverfasser:	Sabet Sarvestani, Fatemeh, Tamaddon, Ali‐Mohammad, Yaghoobi, Ramin, Geramizadeh, Bita, Abolmaali, Samira Sadat, Kaviani, Maryam, Keshtkar, Somayeh, Pakbaz, Sara, Azarpira, Negar
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Autoimmune diseases Biocompatibility Bone marrow bone marrow mesenchymal stem cells Cell culture Coculture Techniques Collagen Collagen - metabolism Dextran Dextrans Diabetes mellitus Gene expression Hydrogels Insulin Insulin - metabolism Insulin secretion Islet cells Islets of Langerhans Laminin Laminin - metabolism Laminin - pharmacology Mesenchymal stem cells Mesenchymal Stem Cells - metabolism MicroRNAs MicroRNAs - metabolism miRNA pancreatic islet Recovery of function Ribonucleic acid RNA Scaffolds Secretion Stem cells Survival Tissue Scaffolds Transplantation Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism
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