Human transthyretin gene expression is markedly increased in repair Schwann cells in an in vitro model of hereditary transthyretin amyloidosis

Hereditary transthyretin (TTR) amyloidosis (ATTRv) is characterized by TTR amyloid deposition in the peripheral nervous system. It remains unknown why variant TTR preferentially deposits in the peripheral nerves and dorsal root ganglia. We previously detected low levels of TTR expression in Schwann...

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Veröffentlicht in:	Neurochemistry international 2023-03, Vol.164, p.105507-105507, Article 105507
Hauptverfasser:	Murakami, Tatsufumi, Ito, Yuri, Sango, Kazunori, Watabe, Kazuhiko, Sunada, Yoshihide
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amyloid Neuropathies, Familial - genetics Amyloidosis Animals Ganglia, Spinal - metabolism Gene Expression Humans Mice Peripheral nerve Prealbumin - genetics Prealbumin - metabolism Repair Schwann cell Schwann Cells - metabolism Transthyretin
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