Ectodysplasin Signaling through XEDAR Is Required for Mammary Gland Morphogenesis

XEDAR is a member of the TNF receptor subfamily and a mediator of the ectodysplasin (EDA) pathway. EDA signaling plays evolutionarily conserved roles in the development of the ectodermal appendage organ class, which includes hair, eccrine sweat glands, and mammary glands. Loss-of-function sequence v...

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Veröffentlicht in:	Journal of investigative dermatology 2023-08, Vol.143 (8), p.1529-1537.e2
Hauptverfasser:	Wark, Abigail R., Aldea, Daniel, Tomizawa, Reiko R., Kokalari, Blerina, Warder, Bailey, Kamberov, Yana G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ectodysplasins - genetics Ectodysplasins - metabolism Membrane Proteins - genetics Mice Morphogenesis Receptors, Tumor Necrosis Factor Signal Transduction
Online-Zugang:	Volltext
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