Dual-Parameter Recognition-Directed Design of the Activatable Fluorescence Probe for Precise Imaging of Cellular Senescence

Specific imaging of cellular senescence emerges as a promising strategy for early diagnosis and treatment of various age-related diseases. The currently available imaging probes are routinely designed by targeting a single senescence-related marker. However, the inherently high heterogeneity of sene...

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Veröffentlicht in:	Analytical chemistry (Washington) 2023-02, Vol.95 (8), p.3996-4004
Hauptverfasser:	Li, Jili, Wang, Linlin, Luo, Xiyuan, Xia, Yinghao, Xie, Yuqi, Liu, Yanlan, Tan, Weihong
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age related diseases Amine oxidase (flavin-containing) Analytical chemistry beta-Galactosidase - metabolism Cellular Senescence Chemistry Design Design parameters Fluorescence Fluorescent Dyes Fluorescent indicators Heterogeneity Medical imaging Monoamine Oxidase Precision medicine Probes Recognition Senescence
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