Aortic Stenosis: Risk Stratification and Timing of Surgery
Purpose of Review This review summarizes the current management of patients with newly diagnosed aortic stenosis. Recent Findings Recent developments include detection of early myocardial dysfunction using serum B-type natriuretic peptide levels and global longitudinal strain, as well as ongoing tri...
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| Veröffentlicht in: | Current cardiology reports 2023-03, Vol.25 (3), p.89-95 |
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| creator | Marcoff, Leo Gillam, Linda D. |
| description | Purpose of Review
This review summarizes the current management of patients with newly diagnosed aortic stenosis.
Recent Findings
Recent developments include detection of early myocardial dysfunction using serum B-type natriuretic peptide levels and global longitudinal strain, as well as ongoing trials of transcatheter aortic valve replacement in asymptomatic patients and patients with moderate aortic stenosis complicated by symptoms or left ventricular systolic dysfunction.
Summary
Given the high mortality associated with severe symptomatic aortic stenosis, all symptomatic patients should be referred for aortic valve replacement. Asymptomatic patients with left ventricular systolic dysfunction, abnormal exercise stress test, high degree of stenosis, rapid disease progression, or elevated serum B-type natriuretic peptide level may also have an indication for valve replacement, based on established criteria. The progress in management of severe aortic stenosis has been in the direction of earlier detection and earlier valve replacement. |
| doi_str_mv | 10.1007/s11886-022-01835-w |
| format | Article |
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This review summarizes the current management of patients with newly diagnosed aortic stenosis.
Recent Findings
Recent developments include detection of early myocardial dysfunction using serum B-type natriuretic peptide levels and global longitudinal strain, as well as ongoing trials of transcatheter aortic valve replacement in asymptomatic patients and patients with moderate aortic stenosis complicated by symptoms or left ventricular systolic dysfunction.
Summary
Given the high mortality associated with severe symptomatic aortic stenosis, all symptomatic patients should be referred for aortic valve replacement. Asymptomatic patients with left ventricular systolic dysfunction, abnormal exercise stress test, high degree of stenosis, rapid disease progression, or elevated serum B-type natriuretic peptide level may also have an indication for valve replacement, based on established criteria. The progress in management of severe aortic stenosis has been in the direction of earlier detection and earlier valve replacement.</description><identifier>ISSN: 1523-3782</identifier><identifier>EISSN: 1534-3170</identifier><identifier>DOI: 10.1007/s11886-022-01835-w</identifier><identifier>PMID: 36787025</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aortic Valve - surgery ; Aortic Valve Stenosis - complications ; Aortic Valve Stenosis - diagnosis ; Aortic Valve Stenosis - surgery ; Cardiology ; Echocardiography (JM Gardin and AH Waller ; Humans ; Medicine ; Medicine & Public Health ; Natriuretic Peptide, Brain ; Risk Assessment ; Section Editors ; Severity of Illness Index ; Topical Collection on Echocardiography ; Ventricular Dysfunction, Left</subject><ispartof>Current cardiology reports, 2023-03, Vol.25 (3), p.89-95</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-5cb155638b8716005f2792c0733f60f8366517769e078f2ee6621d79dacdc5d13</citedby><cites>FETCH-LOGICAL-c347t-5cb155638b8716005f2792c0733f60f8366517769e078f2ee6621d79dacdc5d13</cites><orcidid>0000-0003-1463-885X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11886-022-01835-w$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11886-022-01835-w$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36787025$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Marcoff, Leo</creatorcontrib><creatorcontrib>Gillam, Linda D.</creatorcontrib><title>Aortic Stenosis: Risk Stratification and Timing of Surgery</title><title>Current cardiology reports</title><addtitle>Curr Cardiol Rep</addtitle><addtitle>Curr Cardiol Rep</addtitle><description>Purpose of Review
This review summarizes the current management of patients with newly diagnosed aortic stenosis.
Recent Findings
Recent developments include detection of early myocardial dysfunction using serum B-type natriuretic peptide levels and global longitudinal strain, as well as ongoing trials of transcatheter aortic valve replacement in asymptomatic patients and patients with moderate aortic stenosis complicated by symptoms or left ventricular systolic dysfunction.
Summary
Given the high mortality associated with severe symptomatic aortic stenosis, all symptomatic patients should be referred for aortic valve replacement. Asymptomatic patients with left ventricular systolic dysfunction, abnormal exercise stress test, high degree of stenosis, rapid disease progression, or elevated serum B-type natriuretic peptide level may also have an indication for valve replacement, based on established criteria. The progress in management of severe aortic stenosis has been in the direction of earlier detection and earlier valve replacement.</description><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Stenosis - complications</subject><subject>Aortic Valve Stenosis - diagnosis</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Cardiology</subject><subject>Echocardiography (JM Gardin and AH Waller</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Natriuretic Peptide, Brain</subject><subject>Risk Assessment</subject><subject>Section Editors</subject><subject>Severity of Illness Index</subject><subject>Topical Collection on Echocardiography</subject><subject>Ventricular Dysfunction, Left</subject><issn>1523-3782</issn><issn>1534-3170</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtPAjEUhRujEUT_gAszSzfV25Y-YEeIr4TERHDdDJ2WFGGK7UwI_97iqEs3t_em55zkfAhdE7gjAPI-EaKUwEApBqIYx_sT1CecDTEjEk6PO2WYSUV76CKlNQDNtuE56jEhlQTK-2g8CbHxppg3tg7Jp3Hx5tNHPmPZeOdNnqEuyroqFn7r61URXDFv48rGwyU6c-Um2aufd4DeHx8W02c8e316mU5m2LChbDA3S8K5YGqpJBEA3FE5ogYkY06AU0wITqQUIwtSOWqtEJRUclSVpjK8ImyAbrvcXQyfrU2N3vpk7GZT1ja0SdNs5rk_8CylndTEkFK0Tu-i35bxoAnoIzPdMdOZmf5mpvfZdPOT3y63tvqz_ELKAtYJUv6qc3W9Dm2sc-f_Yr8AjrF1ww</recordid><startdate>20230301</startdate><enddate>20230301</enddate><creator>Marcoff, Leo</creator><creator>Gillam, Linda D.</creator><general>Springer US</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1463-885X</orcidid></search><sort><creationdate>20230301</creationdate><title>Aortic Stenosis: Risk Stratification and Timing of Surgery</title><author>Marcoff, Leo ; Gillam, Linda D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-5cb155638b8716005f2792c0733f60f8366517769e078f2ee6621d79dacdc5d13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Stenosis - complications</topic><topic>Aortic Valve Stenosis - diagnosis</topic><topic>Aortic Valve Stenosis - surgery</topic><topic>Cardiology</topic><topic>Echocardiography (JM Gardin and AH Waller</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Natriuretic Peptide, Brain</topic><topic>Risk Assessment</topic><topic>Section Editors</topic><topic>Severity of Illness Index</topic><topic>Topical Collection on Echocardiography</topic><topic>Ventricular Dysfunction, Left</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marcoff, Leo</creatorcontrib><creatorcontrib>Gillam, Linda D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current cardiology reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marcoff, Leo</au><au>Gillam, Linda D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aortic Stenosis: Risk Stratification and Timing of Surgery</atitle><jtitle>Current cardiology reports</jtitle><stitle>Curr Cardiol Rep</stitle><addtitle>Curr Cardiol Rep</addtitle><date>2023-03-01</date><risdate>2023</risdate><volume>25</volume><issue>3</issue><spage>89</spage><epage>95</epage><pages>89-95</pages><issn>1523-3782</issn><eissn>1534-3170</eissn><abstract>Purpose of Review
This review summarizes the current management of patients with newly diagnosed aortic stenosis.
Recent Findings
Recent developments include detection of early myocardial dysfunction using serum B-type natriuretic peptide levels and global longitudinal strain, as well as ongoing trials of transcatheter aortic valve replacement in asymptomatic patients and patients with moderate aortic stenosis complicated by symptoms or left ventricular systolic dysfunction.
Summary
Given the high mortality associated with severe symptomatic aortic stenosis, all symptomatic patients should be referred for aortic valve replacement. Asymptomatic patients with left ventricular systolic dysfunction, abnormal exercise stress test, high degree of stenosis, rapid disease progression, or elevated serum B-type natriuretic peptide level may also have an indication for valve replacement, based on established criteria. The progress in management of severe aortic stenosis has been in the direction of earlier detection and earlier valve replacement.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>36787025</pmid><doi>10.1007/s11886-022-01835-w</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-1463-885X</orcidid></addata></record> |
| fulltext | fulltext |
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| ispartof | Current cardiology reports, 2023-03, Vol.25 (3), p.89-95 |
| issn | 1523-3782 1534-3170 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Aortic Valve - surgery Aortic Valve Stenosis - complications Aortic Valve Stenosis - diagnosis Aortic Valve Stenosis - surgery Cardiology Echocardiography (JM Gardin and AH Waller Humans Medicine Medicine & Public Health Natriuretic Peptide, Brain Risk Assessment Section Editors Severity of Illness Index Topical Collection on Echocardiography Ventricular Dysfunction, Left |
| title | Aortic Stenosis: Risk Stratification and Timing of Surgery |
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