Oxysterol-binding protein-like 3 is a novel target gene of peroxisome proliferator-activated receptor γ in fatty liver disease

Oxysterol-binding protein-like 3 (OSBPL3) plays a key role in the development of fatty liver disease. Herein, we found that OSBPL3 is highly expressed in the fatty liver of humans and mice. Although high expression of Osbpl3 was observed in the fatty liver of type 2 diabetic ob/ob mice, liver-specif...

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Veröffentlicht in:	Molecular and cellular endocrinology 2023-04, Vol.565, p.111887-111887, Article 111887
Hauptverfasser:	Aibara, Daisuke, Sakaguchi, Ai, Matsusue, Kimihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ethanol - metabolism Fatty liver disease Humans Liver - metabolism Mice Mice, Inbred C57BL NAFLD Non-alcoholic Fatty Liver Disease - metabolism Nuclear receptor OSBPL3 Oxysterols - metabolism PPAR gamma - metabolism PPARγ
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