Preparation, characterization, and pharmacokinetics of oridonin‐loaded liposomes

The aim of this study was to prepare oridonin liposomes and evaluate the physicochemical characteristics and pharmacokinetics in rats. A three‐level, three‐factor Box–Behnken design was used to optimize the preparation of oridonin liposomes. A highly sensitive high‐performance liquid chromatographic...

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Veröffentlicht in:	Biomedical chromatography 2023-05, Vol.37 (5), p.e5603-n/a
Hauptverfasser:	Lin, Fei‐er, Zhang, Xin‐yan, Zhang, Yu‐ping, Wang, Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Diterpenes, Kaurane - pharmacokinetics liposomes Liposomes - chemistry Liposomes - pharmacokinetics oridonin Particle Size pharmacokinetics Phospholipids - chemistry Rats Rats, Sprague-Dawley
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