Effect of high-dose statin therapy on coagulation factors: Lowering of factor XI as a modifier of fibrin clot properties in coronary artery disease

Multiple pleiotropic effects of statins include antithrombotic properties with formation of looser fibrin networks more susceptible to lysis. Recently, rosuvastatin 20 mg/d has been reported to decrease coagulation factors (F) VII, FVIII and FXI in venous thrombosis patients. We investigated how hig...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vascular pharmacology 2023-04, Vol.149, p.107153-107153, Article 107153
Hauptverfasser:	Stępień, Konrad, Siudut, Jakub, Konieczyńska, Małgorzata, Nowak, Karol, Zalewski, Jarosław, Undas, Anetta
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Coagulation Factors Cholesterol, LDL Coagulation factor Coronary artery disease Coronary Artery Disease - diagnosis Coronary Artery Disease - drug therapy Factor XI Fibrin Fibrin clot Fibrinolytic Agents Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects Rosuvastatin Calcium - adverse effects Statin Thrombin Thrombin generation Thrombosis - diagnosis Thrombosis - drug therapy Thrombosis - prevention & control
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!