Targeting galectin-driven regulatory circuits in cancer and fibrosis

Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a broad range of physiological and pathological processes. As a group, these proteins use both extracellular and intracellular mechanisms as well as glycan-dependent and independent pathways to reprogramme the fa...

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Veröffentlicht in:Nature reviews. Drug discovery 2023-04, Vol.22 (4), p.295-316
Hauptverfasser: Mariño, Karina V., Cagnoni, Alejandro J., Croci, Diego O., Rabinovich, Gabriel A.
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Sprache:eng
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