Bioisosterism: 1,2,4‐Oxadiazole Rings

Although studies in drug discovery have gained momentum in recent years, the conversion of drugs in use today into less toxic derivatives with pharmacologically superior properties is still of great importance in drug research. Bioisosterism facilitates the conversion of drugs into derivatives that...

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Veröffentlicht in:	ChemMedChem 2023-05, Vol.18 (9), p.e202200638-n/a
Hauptverfasser:	Camci, Merve, Karali, Nilgün
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2,4-oxadiazoles Amides Amides - chemistry bioisosterism Conversion Drug development Drug Discovery Drugs Esters Functional groups medicinal chemistry Oxadiazoles Oxadiazoles - chemistry Oxadiazoles - pharmacology Pharmacology Structure-Activity Relationship structure-activity relationships Toxicology
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